SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ko7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.91A 1dz4A-3ko7A:
undetectable
1dz4A-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.93A 1dz4B-3ko7A:
undetectable
1dz4B-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 8 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.94A 1iwiA-3ko7A:
undetectable
1iwiA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.97A 1t85A-3ko7A:
undetectable
1t85A-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.95A 1t87A-3ko7A:
undetectable
1t87A-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.00A 1yrcA-3ko7A:
undetectable
1yrcA-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.02A 2cppA-3ko7A:
undetectable
2cppA-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.02A 2feuB-3ko7A:
undetectable
2feuB-3ko7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.97A 2qblA-3ko7A:
undetectable
2qblA-3ko7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 GLN A 126
ILE A  85
TYR A 127
CYH A  39
None
1.43A 2xz5D-3ko7A:
undetectable
2xz5E-3ko7A:
undetectable
2xz5D-3ko7A:
20.61
2xz5E-3ko7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.94A 2zawA-3ko7A:
undetectable
2zawA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.04A 3fwfA-3ko7A:
undetectable
3fwfA-3ko7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.01A 3fwgA-3ko7A:
undetectable
3fwgA-3ko7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.99A 3fwgB-3ko7A:
undetectable
3fwgB-3ko7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.00A 3wrhA-3ko7A:
undetectable
3wrhA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.02A 3wrhE-3ko7A:
undetectable
3wrhE-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.00A 3wrjA-3ko7A:
undetectable
3wrjA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.01A 3wrjE-3ko7A:
undetectable
3wrjE-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.03A 3wrlA-3ko7A:
undetectable
3wrlA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.98A 3wrmF-3ko7A:
undetectable
3wrmF-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
3 / 3 TYR A 140
MET A 141
ILE A  85
None
0.77A 4c8bB-3ko7A:
undetectable
4c8bB-3ko7A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
3 / 3 ARG A   7
THR A  71
TRP A  72
None
1.22A 4d7hA-3ko7A:
undetectable
4d7hA-3ko7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.01A 4g3rA-3ko7A:
undetectable
4g3rA-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.96A 4g3rB-3ko7A:
undetectable
4g3rB-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.94A 4kkyX-3ko7A:
undetectable
4kkyX-3ko7A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 6 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
1.03A 4l4cA-3ko7A:
undetectable
4l4cA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
4 / 7 LEU A  79
VAL A  76
VAL A 151
ASP A 148
None
0.98A 4l4gA-3ko7A:
undetectable
4l4gA-3ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
3 / 3 ARG A   7
THR A  71
TRP A  72
None
1.15A 4ug5A-3ko7A:
undetectable
4ug5A-3ko7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
3 / 3 ARG A   7
THR A  71
TRP A  72
None
1.20A 4uglA-3ko7A:
undetectable
4uglA-3ko7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum)
3 / 3 ARG A   7
THR A  71
TRP A  72
None
1.21A 5g6cA-3ko7A:
undetectable
5g6cA-3ko7A:
18.75