SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		4 / 8 TYR A  53
GLN A 105
ILE A 107
SER A  40
 None
 0.81A 2xz5B-3kopA:
undetectable
2xz5E-3kopA:
undetectable		 2xz5B-3kopA:
22.57
2xz5E-3kopA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		5 / 12 ASN A   6
THR A   8
VAL A 137
LEU A  19
ILE A 136
 None
 1.46A 3elzC-3kopA:
undetectable		 3elzC-3kopA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		5 / 12 VAL A  32
LEU A  36
VAL A  78
ALA A 134
LEU A  20
 None
 1.09A 3nt1A-3kopA:
undetectable		 3nt1A-3kopA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		5 / 12 VAL A  32
LEU A  36
VAL A  78
ALA A 134
LEU A  20
 None
 1.09A 3nt1B-3kopA:
undetectable		 3nt1B-3kopA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		5 / 12 VAL A  32
LEU A  36
VAL A  78
ALA A 134
LEU A  20
 None
 1.08A 3pghD-3kopA:
undetectable		 3pghD-3kopA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		4 / 6 ASP A 109
LEU A  55
TYR A  53
GLU A  51
 None
 1.04A 3w9tB-3kopA:
undetectable		 3w9tB-3kopA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		4 / 6 ASP A 109
LEU A  55
TYR A  53
GLU A  51
 None
 1.03A 3w9tE-3kopA:
undetectable		 3w9tE-3kopA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		4 / 6 ASP A 109
LEU A  55
TYR A  53
GLU A  51
 None
 1.04A 3w9tF-3kopA:
undetectable		 3w9tF-3kopA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_A_ACTA301_0
(ANTIBODY FAB HEAVY
CHAIN)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		4 / 4 THR A 106
VAL A 108
PRO A  64
THR A  82
 None
 1.15A 5mthA-3kopA:
undetectable
5mthH-3kopA:
undetectable		 5mthA-3kopA:
20.75
5mthH-3kopA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3kop UNCHARACTERIZED
PROTEIN
(Arthrobacter
sp.
FB24) 		5 / 12 LEU A  88
ALA A 111
PHE A  81
PRO A  73
LEU A 120
 None
 1.17A 5nd2B-3kopA:
undetectable		 5nd2B-3kopA:
19.20