SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3koy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 7 PHE A  87
VAL A 130
ILE A 105
TYR A 157
 None
 0.85A 11gsA-3koyA:
undetectable		 11gsA-3koyA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 LEU A 570
GLU A 537
THR A 566
LEU A 525
 None
 1.28A 1etb2-3koyA:
undetectable		 1etb2-3koyA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 LEU A  55
ASP A 103
ILE A 105
GLU A 148
ARG A  29
 None
 1.37A 1l7gA-3koyA:
undetectable		 1l7gA-3koyA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 8 GLY A 720
SER A 667
ASP A 616
THR A 612
 None
B12  A1801 (-2.5A)
None
None
 0.72A 1m4iA-3koyA:
undetectable		 1m4iA-3koyA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 PRO A 124
THR A 133
ILE A 108
GLY A 129
GLY A 126
 5AD  A1500 ( 4.8A)
None
None
None
None
 0.98A 1nv8A-3koyA:
undetectable		 1nv8A-3koyA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q72_H_COCH401_1
(FAB M82G2, HEAVY
CHAIN
FAB M82G2, LIGHT
CHAIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 10 VAL A 130
GLY A 129
HIS A 182
TYR A 160
TYR A 157
 None
None
Z97  A 767 (-4.0A)
Z97  A 767 (-4.7A)
None
 1.46A 1q72H-3koyA:
2.2
1q72L-3koyA:
0.0		 1q72H-3koyA:
14.70
1q72L-3koyA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 PRO A 124
THR A 133
ILE A 108
GLY A 129
GLY A 126
 5AD  A1500 ( 4.8A)
None
None
None
None
 0.97A 1sg9B-3koyA:
undetectable		 1sg9B-3koyA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ARG A 498
SER A  84
GLY A 129
THR A 110
 None
 1.04A 2f7fA-3koyA:
4.3		 2f7fA-3koyA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 ILE A 432
GLY A 431
VAL A 405
ASN A 188
PRO A 185
 None
 1.06A 2okcA-3koyA:
undetectable		 2okcA-3koyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 ILE A 432
GLY A 431
VAL A 405
ASN A 188
PRO A 185
 None
 1.05A 2okcB-3koyA:
undetectable		 2okcB-3koyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 LEU A  61
ASP A  71
ALA A  60
ILE A 360
 None
 1.16A 2qhfA-3koyA:
undetectable		 2qhfA-3koyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 9 PHE A  87
PRO A 131
VAL A 130
ILE A 105
TYR A 157
 None
 1.32A 3csjB-3koyA:
undetectable		 3csjB-3koyA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 ILE A 105
ILE A 155
GLY A 152
LEU A   7
ARG A  95
 None
 1.08A 3em0B-3koyA:
undetectable		 3em0B-3koyA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		3 / 3 HIS A 104
HIS A 158
MET A 106
 None
None
Z97  A 767 ( 4.1A)
 0.82A 3mihA-3koyA:
undetectable		 3mihA-3koyA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 11 LEU A 190
VAL A 405
ALA A 404
PHE A 391
ARG A 387
 None
 1.29A 3n23C-3koyA:
0.8		 3n23C-3koyA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 4 LEU A 377
GLY A 375
GLY A 378
THR A 380
 None
 0.88A 3si7A-3koyA:
undetectable		 3si7A-3koyA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 11 GLY A 166
ALA A 216
GLY A 180
ASN A 261
MET A 257
 None
 1.34A 4a6nA-3koyA:
undetectable		 4a6nA-3koyA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 ILE A 541
ILE A 555
ASN A 556
MET A 527
LEU A 529
 None
 1.03A 4a84A-3koyA:
undetectable		 4a84A-3koyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 TYR A 416
PHE A 391
VAL A 405
GLN A 186
TYR A 401
 None
 1.43A 4a99A-3koyA:
undetectable
4a99C-3koyA:
undetectable		 4a99A-3koyA:
19.53
4a99C-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 ILE A 726
ILE A 633
TYR A 636
GLU A 634
 None
 1.25A 4a99D-3koyA:
undetectable		 4a99D-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 12 LEU A  55
ASP A 103
ILE A 105
GLU A 148
ARG A  29
 None
 1.38A 4mwvA-3koyA:
undetectable		 4mwvA-3koyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		3 / 3 MET A 296
MET A 300
TYR A 283
 None
 1.37A 4p6xI-3koyA:
undetectable		 4p6xI-3koyA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 7 PRO A 336
GLU A 350
GLU A 569
THR A 566
 None
 1.26A 4uacA-3koyA:
undetectable		 4uacA-3koyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		3 / 3 ASP A  71
ARG A  35
PRO A  74
 None
 1.02A 4wanC-3koyA:
undetectable		 4wanC-3koyA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 GLY A 521
ARG A 573
GLY A 572
GLU A 551
 None
 1.07A 4z2eB-3koyA:
undetectable
4z2eC-3koyA:
4.0		 4z2eB-3koyA:
22.39
4z2eC-3koyA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 7 ASP A 627
ARG A 623
GLY A 621
THR A 645
 None
None
B12  A1801 (-3.3A)
None
 0.94A 5btaA-3koyA:
undetectable
5btaC-3koyA:
undetectable
5btaD-3koyA:
3.6		 5btaA-3koyA:
22.40
5btaC-3koyA:
22.40
5btaD-3koyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 7 ASP A 627
ARG A 623
GLY A 621
THR A 645
 None
None
B12  A1801 (-3.3A)
None
 0.90A 5btfA-3koyA:
undetectable
5btfB-3koyA:
3.9
5btfC-3koyA:
undetectable		 5btfA-3koyA:
22.40
5btfB-3koyA:
18.36
5btfC-3koyA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 7 ASP A 627
ARG A 623
GLY A 621
THR A 645
 None
None
B12  A1801 (-3.3A)
None
 0.77A 5btgA-3koyA:
undetectable
5btgC-3koyA:
undetectable
5btgD-3koyA:
3.6		 5btgA-3koyA:
22.40
5btgC-3koyA:
22.40
5btgD-3koyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 LEU A 665
ARG A 693
ILE A 664
ILE A 696
 B12  A1801 ( 3.8A)
None
None
None
 1.03A 5dzk4-3koyA:
undetectable
5dzkg-3koyA:
2.5
5dzkm-3koyA:
undetectable
5dzkn-3koyA:
undetectable		 5dzk4-3koyA:
0.63
5dzkg-3koyA:
14.80
5dzkm-3koyA:
14.08
5dzkn-3koyA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 0.94A 5eckA-3koyA:
undetectable		 5eckA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 0.95A 5eckD-3koyA:
undetectable		 5eckD-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.00A 5eclA-3koyA:
undetectable		 5eclA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 ALA A 181
VAL A 178
TYR A 157
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.00A 5ecoA-3koyA:
undetectable		 5ecoA-3koyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 GLY A 702
THR A 703
SER A 667
HIS A 618
 B12  A1801 (-3.1A)
B12  A1801 (-3.2A)
B12  A1801 (-2.5A)
B12  A1801 (-3.7A)
 0.89A 5ewuA-3koyA:
undetectable		 5ewuA-3koyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 GLY A 702
THR A 703
SER A 667
HIS A 618
 B12  A1801 (-3.1A)
B12  A1801 (-3.2A)
B12  A1801 (-2.5A)
B12  A1801 (-3.7A)
 0.94A 5ewuB-3koyA:
undetectable		 5ewuB-3koyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 CYH A 263
ILE A 330
HIS A 158
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.39A 5ocsA-3koyA:
10.0		 5ocsA-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 CYH A 263
ILE A 330
HIS A 158
HIS A 182
 None
None
None
Z97  A 767 (-4.0A)
 1.39A 5ocsC-3koyA:
6.7		 5ocsC-3koyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		3 / 3 CYH A 700
MET A 680
ASN A 679
 None
 1.35A 5qh8A-3koyA:
undetectable		 5qh8A-3koyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 CYH A 263
SER A 265
HIS A 158
TYR A 160
 None
Z97  A 767 ( 4.6A)
None
Z97  A 767 (-4.7A)
 1.21A 5ycnA-3koyA:
undetectable		 5ycnA-3koyA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		5 / 9 VAL A 243
GLY A 408
VAL A 405
ASP A 412
GLY A 423
 None
 1.38A 5zniA-3koyA:
undetectable		 5zniA-3koyA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 GLY A  31
ASN A 179
ARG A  30
ARG A 141
 None
 1.37A 6dwdB-3koyA:
undetectable
6dwdD-3koyA:
undetectable		 6dwdB-3koyA:
21.13
6dwdD-3koyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 5 ARG A  30
ARG A 141
GLY A  31
ASN A 179
 None
 1.41A 6dwjB-3koyA:
undetectable
6dwjD-3koyA:
undetectable		 6dwjB-3koyA:
21.13
6dwjD-3koyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3koy D-ORNITHINE
AMINOMUTASE E
COMPONENT
(Acetoanaerobium
sticklandii) 		4 / 6 GLU A  88
ARG A 498
VAL A 130
PRO A 131
 None
 1.40A 6fgdA-3koyA:
undetectable		 6fgdA-3koyA:
19.58