SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kpt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		4 / 8 TYR A 220
GLU A 196
PHE A 190
VAL A 211
 None
 1.15A 2fl5E-3kptA:
2.6
2fl5F-3kptA:
2.8		 2fl5E-3kptA:
20.73
2fl5F-3kptA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		4 / 5 TYR A 308
GLU A 267
ASP A 301
ASP A 233
 None
 1.36A 2yqzA-3kptA:
undetectable		 2yqzA-3kptA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		4 / 5 TYR A 308
GLU A 267
ASP A 301
ASP A 233
 None
 1.32A 2yqzB-3kptA:
undetectable		 2yqzB-3kptA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 ARG A 237
PRO A 227
PHE A 187
 None
 0.97A 3thrC-3kptA:
undetectable		 3thrC-3kptA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		4 / 8 LYS A 507
THR A 416
SER A 461
VAL A 457
 None
 0.69A 4ik7B-3kptA:
9.2		 4ik7B-3kptA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 SER A 244
ALA A 169
VAL A 170
 None
 0.61A 4o2bA-3kptA:
undetectable		 4o2bA-3kptA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 SER A 244
ALA A 169
VAL A 170
 None
 0.59A 4o2bC-3kptA:
undetectable		 4o2bC-3kptA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 SER A 244
ALA A 169
VAL A 170
 None
 0.43A 4x1iA-3kptA:
undetectable		 4x1iA-3kptA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 SER A 244
ALA A 169
VAL A 170
 None
 0.43A 5eypA-3kptA:
undetectable		 5eypA-3kptA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		3 / 3 GLN A 222
ILE A 173
HIS A 208
 None
 0.70A 5z12B-3kptA:
undetectable		 5z12B-3kptA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 298
LEU A 365
VAL A 337
VAL A 338
THR A 355
 None
 0.89A 6b52A-3kptA:
undetectable		 6b52A-3kptA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		5 / 11 ILE A 381
PRO A 408
PRO A 286
LEU A 318
SER A 369
 None
 1.31A 6dlzA-3kptA:
undetectable
6dlzD-3kptA:
undetectable		 6dlzA-3kptA:
12.15
6dlzD-3kptA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3kpt COLLAGEN ADHESION
PROTEIN
(Bacillus
cereus) 		5 / 11 ILE A 381
PRO A 408
PRO A 286
LEU A 318
SER A 369
 None
 1.31A 6dm1A-3kptA:
undetectable
6dm1D-3kptA:
undetectable		 6dm1A-3kptA:
12.15
6dm1D-3kptA:
12.15