SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 TYR A 110
LEU A 102
LEU A 101
ALA A  99
 None
None
None
JIM  A 193 ( 4.0A)
 0.81A 2wekA-3kq0A:
undetectable		 2wekA-3kq0A:
21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		8 / 12 PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
ALA A  99
SER A 125
TYR A 127
 JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
None
 0.80A 3apvA-3kq0A:
27.8		 3apvA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  51
HIS A  97
ALA A  99
SER A 125
TYR A 127
 None
None
JIM  A 193 ( 4.0A)
None
None
 0.76A 3apvA-3kq0A:
27.8		 3apvA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  51
LEU A  62
ARG A  90
ALA A  99
TYR A 110
 None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
 1.46A 3apvA-3kq0A:
27.8		 3apvA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  51
LEU A  79
HIS A  97
SER A 125
TYR A 127
 None
 1.34A 3apvA-3kq0A:
27.8		 3apvA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		8 / 12 VAL A  41
PHE A  49
PHE A  51
LEU A  62
ARG A  90
ALA A  99
SER A 125
TYR A 127
 None
JIM  A 193 (-3.8A)
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
None
 0.70A 3apvA-3kq0A:
27.8		 3apvA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		7 / 12 PHE A  32
PHE A  49
PHE A  51
HIS A  97
ALA A  99
SER A 125
TYR A 127
 None
JIM  A 193 (-3.8A)
None
None
JIM  A 193 ( 4.0A)
None
None
 0.89A 3apvB-3kq0A:
28.1		 3apvB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		6 / 12 PHE A  32
PHE A  51
LEU A  79
HIS A  97
SER A 125
TYR A 127
 None
 1.29A 3apvB-3kq0A:
28.1		 3apvB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		9 / 12 PHE A  32
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ALA A  99
SER A 125
TYR A 127
 None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 ( 4.0A)
None
None
 0.68A 3apvB-3kq0A:
28.1		 3apvB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		8 / 12 PHE A  32
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
ALA A  99
 None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
 0.91A 3apvB-3kq0A:
28.1		 3apvB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  51
LEU A  62
ARG A  90
ALA A  99
TYR A 110
 None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
 1.44A 3apvB-3kq0A:
28.1		 3apvB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		10 / 12 TYR A  27
PHE A  32
VAL A  41
ILE A  44
PHE A  49
PHE A  51
GLU A  64
ALA A  99
SER A 125
TYR A 127
 None
None
None
None
JIM  A 193 (-3.8A)
None
None
JIM  A 193 ( 4.0A)
None
None
 0.73A 3apwA-3kq0A:
28.0		 3apwA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		9 / 12 VAL A  41
ILE A  44
PHE A  49
PHE A  51
LEU A  62
GLN A  66
ARG A  90
SER A 125
TYR A 127
 None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
None
None
 0.74A 3apwB-3kq0A:
27.6		 3apwB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		10 / 12 VAL A  41
ILE A  44
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
ALA A  99
SER A 125
TYR A 127
 None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
None
 0.64A 3apwB-3kq0A:
27.6		 3apwB-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		9 / 12 PHE A  32
VAL A  41
THR A  47
PHE A  49
PHE A  51
GLU A  64
LEU A  79
ALA A  99
TYR A 127
 None
None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 ( 4.0A)
None
 0.84A 3apxA-3kq0A:
27.6		 3apxA-3kq0A:
86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		9 / 12 PHE A  32
VAL A  41
THR A  47
PHE A  49
PHE A  51
GLU A  64
LEU A  79
ARG A  90
TYR A 127
 None
None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
None
 0.86A 3apxA-3kq0A:
27.6		 3apxA-3kq0A:
86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 7 PHE A  32
TYR A  37
VAL A  41
ILE A  44
 None
 1.08A 4a97E-3kq0A:
undetectable		 4a97E-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 PHE A  32
TYR A  37
VAL A  41
ILE A  44
 None
 1.06A 4a97D-3kq0A:
undetectable		 4a97D-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 PHE A  32
TYR A  37
VAL A  41
ILE A  44
 None
 1.08A 4a97G-3kq0A:
undetectable		 4a97G-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 7 PHE A  32
TYR A  37
VAL A  41
ILE A  44
 None
 1.06A 4a97H-3kq0A:
undetectable		 4a97H-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 PHE A  32
TYR A  37
VAL A  41
ILE A  44
 None
 1.00A 4a97I-3kq0A:
undetectable		 4a97I-3kq0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 TYR A 127
TYR A 110
LEU A  62
LEU A  79
 None
 1.06A 4jtrA-3kq0A:
undetectable		 4jtrA-3kq0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		4 / 8 TYR A 127
TYR A 110
LEU A  62
LEU A  79
 None
 0.90A 4l1xA-3kq0A:
undetectable		 4l1xA-3kq0A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens) 		5 / 11 TYR A 127
LEU A 101
TYR A 110
LEU A  62
LEU A  79
 None
 1.43A 4yvpA-3kq0A:
undetectable		 4yvpA-3kq0A:
20.55