SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3krn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 ASP A 212
VAL A 211
SER A 210
ASP A 118
 None
 1.46A 1n2xB-3krnA:
undetectable		 1n2xB-3krnA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NN0_X_NCAX433_0
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 9 ASN A 110
LEU A 131
LEU A   5
PHE A  24
GLY A 102
 None
 1.27A 3nn0X-3krnA:
0.0		 3nn0X-3krnA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 6 SER A 193
GLY A 129
ASN A 110
ILE A 132
 None
 1.16A 5j4nA-3krnA:
undetectable		 5j4nA-3krnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		3 / 3 ASN A 110
TYR A 201
CYH A  10
 None
 0.92A 5lsuB-3krnA:
undetectable		 5lsuB-3krnA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 3krn PROTEIN C14A4.5,
CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 GLY A 129
LEU A 156
GLY A  97
ASP A 100
ASN A  71
 None
 1.15A 6gngA-3krnA:
undetectable		 6gngA-3krnA:
15.62