SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ks2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		4 / 7 ALA A  96
TYR A  93
TYR A  44
TYR A  40
 None
 1.18A 2ajvH-3ks2A:
undetectable
2ajvL-3ks2A:
undetectable		 2ajvH-3ks2A:
20.09
2ajvL-3ks2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		4 / 7 PHE A  97
TYR A  93
PRO A 106
THR A 110
 None
 1.38A 2q6kA-3ks2A:
undetectable		 2q6kA-3ks2A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		5 / 10 VAL A 107
PHE A 108
GLN A 112
ILE A 150
LEU A 129
 None
 1.03A 3gwxA-3ks2A:
undetectable		 3gwxA-3ks2A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		4 / 8 ILE A 131
LYS A 140
ILE A 141
ASP A 148
 None
 0.94A 4dtaB-3ks2A:
undetectable		 4dtaB-3ks2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		5 / 9 LEU A 117
GLN A 114
ALA A  89
ASP A  91
ALA A  94
 None
 1.49A 4wnuB-3ks2A:
undetectable		 4wnuB-3ks2A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3ks2 CHAPERONE PROTEIN
IPGC
(Shigella
flexneri) 		5 / 12 PHE A 127
ALA A 123
TYR A  93
MET A  74
LEU A 139
 None
 1.39A 5ljbA-3ks2A:
undetectable		 5ljbA-3ks2A:
21.64