SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ks5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 VAL A 199
ILE A 181
ARG A   3
LEU A 195
 None
 0.97A 1iepB-3ks5A:
undetectable		 1iepB-3ks5A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ILE A  76
ALA A  74
ILE A  63
PRO A  84
 None
 0.74A 1oniB-3ks5A:
undetectable
1oniC-3ks5A:
undetectable		 1oniB-3ks5A:
20.00
1oniC-3ks5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 7 ALA A 202
ILE A 173
ILE A 184
ASP A 205
PHE A 206
 None
None
None
ACT  A 254 (-3.7A)
None
 1.37A 1upfB-3ks5A:
undetectable		 1upfB-3ks5A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 10 HIS A 212
ALA A 220
HIS A   7
THR A 230
ILE A 217
 None
None
ACT  A 252 ( 3.6A)
None
None
 1.34A 1utdQ-3ks5A:
undetectable
1utdR-3ks5A:
undetectable		 1utdQ-3ks5A:
14.74
1utdR-3ks5A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		3 / 3 GLU A 104
HIS A   7
GLU A  34
 FE  A 250 (-3.3A)
ACT  A 252 ( 3.6A)
FE  A 250 ( 2.6A)
 0.74A 2x45B-3ks5A:
undetectable		 2x45B-3ks5A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		3 / 3 GLU A 104
HIS A   7
GLU A  34
 FE  A 250 (-3.3A)
ACT  A 252 ( 3.6A)
FE  A 250 ( 2.6A)
 0.77A 2x45C-3ks5A:
undetectable		 2x45C-3ks5A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 5 ILE A 122
THR A 151
THR A 152
PHE A 136
 None
 1.04A 3snfA-3ks5A:
undetectable		 3snfA-3ks5A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 PHE A 136
THR A 152
ARG A 155
PRO A 154
 None
 1.10A 3tzfB-3ks5A:
11.7		 3tzfB-3ks5A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 SER A  17
GLU A  34
LEU A  37
VAL A  47
 None
FE  A 250 ( 2.6A)
None
None
 0.88A 3ua5B-3ks5A:
undetectable		 3ua5B-3ks5A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.12A 4feuB-3ks5A:
undetectable		 4feuB-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.10A 4feuD-3ks5A:
undetectable		 4feuD-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.11A 4feuF-3ks5A:
undetectable		 4feuF-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.13A 4fevB-3ks5A:
undetectable		 4fevB-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.09A 4fevD-3ks5A:
undetectable		 4fevD-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.10A 4fevF-3ks5A:
undetectable		 4fevF-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.11A 4fewB-3ks5A:
undetectable		 4fewB-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.09A 4fewD-3ks5A:
undetectable		 4fewD-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.14A 4fewF-3ks5A:
undetectable		 4fewF-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.13A 4fexB-3ks5A:
undetectable		 4fexB-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.10A 4gkhB-3ks5A:
undetectable		 4gkhB-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.11A 4gkhF-3ks5A:
undetectable		 4gkhF-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.13A 4gkhG-3ks5A:
undetectable		 4gkhG-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 6 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.13A 4gkhJ-3ks5A:
undetectable		 4gkhJ-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.12A 4gkhC-3ks5A:
undetectable
4gkhK-3ks5A:
undetectable		 4gkhC-3ks5A:
23.30
4gkhK-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.10A 4gkiA-3ks5A:
undetectable		 4gkiA-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  36
ASP A  50
ASP A 231
ASP A  16
 FE  A 250 (-2.6A)
EDO  A 256 (-3.0A)
None
EDO  A 256 (-3.5A)
 1.12A 4gkiC-3ks5A:
undetectable		 4gkiC-3ks5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASP A  42
MET A  85
VAL A  46
THR A  86
 None
 1.10A 4lnwA-3ks5A:
undetectable		 4lnwA-3ks5A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 9 THR A  25
THR A 234
ALA A 236
GLY A   9
GLY A  10
 None
 1.18A 4qwuK-3ks5A:
undetectable
4qwuL-3ks5A:
undetectable		 4qwuK-3ks5A:
20.82
4qwuL-3ks5A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 6 ASP A  16
ARG A   8
GLY A   9
GLU A  34
 EDO  A 256 (-3.5A)
ACT  A 251 ( 3.9A)
None
FE  A 250 ( 2.6A)
 1.00A 5cdqA-3ks5A:
undetectable
5cdqC-3ks5A:
undetectable
5cdqD-3ks5A:
undetectable		 5cdqA-3ks5A:
20.25
5cdqC-3ks5A:
20.25
5cdqD-3ks5A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 9 ASP A  16
GLY A  10
GLY A   9
ALA A   5
VAL A  33
 EDO  A 256 (-3.5A)
None
None
None
None
 1.10A 5v3cA-3ks5A:
8.9		 5v3cA-3ks5A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3ks5 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 VAL A 121
ALA A 210
ARG A   8
PHE A  35
LEU A  37
 None
None
ACT  A 251 ( 3.9A)
None
None
 1.39A 6a7pB-3ks5A:
undetectable		 6a7pB-3ks5A:
16.58