SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ks7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 LEU A 278
SER A 302
ASN A 310
 None
 0.83A 1bx4A-3ks7A:
undetectable		 1bx4A-3ks7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 GLU A 373
TYR A 280
PHE A 311
PRO A 313
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
EDO  A 420 (-4.5A)
 1.02A 1dfoB-3ks7A:
undetectable		 1dfoB-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 GLU A 373
TYR A 280
PHE A 311
PRO A 313
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
EDO  A 420 (-4.5A)
 1.02A 1dfoA-3ks7A:
undetectable		 1dfoA-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 GLU A 373
TYR A 280
PHE A 311
PRO A 313
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
EDO  A 420 (-4.5A)
 1.02A 1dfoD-3ks7A:
undetectable		 1dfoD-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 GLU A 373
TYR A 280
PHE A 311
PRO A 313
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
EDO  A 420 (-4.5A)
 1.02A 1dfoC-3ks7A:
undetectable		 1dfoC-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_2
(DIHYDROFOLATE
REDUCTASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 4 TYR A 248
ARG A  68
VAL A 137
THR A 148
 None
 1.20A 1dlsA-3ks7A:
0.0		 1dlsA-3ks7A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 GLU A 373
TYR A 280
PHE A 311
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
 0.96A 1eqbB-3ks7A:
undetectable		 1eqbB-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 GLU A 373
TYR A 280
PHE A 311
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
 0.95A 1eqbA-3ks7A:
undetectable		 1eqbA-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 GLU A 373
TYR A 280
PHE A 311
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
 0.95A 1eqbD-3ks7A:
undetectable		 1eqbD-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 GLU A 373
TYR A 280
PHE A 311
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
 0.95A 1eqbC-3ks7A:
undetectable		 1eqbC-3ks7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 ARG A 229
GLY A  30
ASP A  31
TYR A  79
 None
 1.17A 1kf6M-3ks7A:
undetectable
1kf6N-3ks7A:
undetectable		 1kf6M-3ks7A:
20.73
1kf6N-3ks7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 8 VAL A 247
TYR A 248
ASP A 210
LEU A 115
 None
 1.25A 1pk2A-3ks7A:
undetectable		 1pk2A-3ks7A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 ASP A 369
GLU A 373
TYR A 410
 None
EDO  A 420 ( 3.5A)
None
 0.85A 1wsvA-3ks7A:
undetectable		 1wsvA-3ks7A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		5 / 11 PHE A 154
ILE A 207
GLY A 206
ILE A 223
LEU A  87
 None
 1.05A 1z11B-3ks7A:
undetectable		 1z11B-3ks7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		5 / 10 PHE A 154
ILE A 207
GLY A 206
ILE A 223
LEU A  87
 None
 1.11A 1z11D-3ks7A:
undetectable		 1z11D-3ks7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 PHE A 154
VAL A  89
TRP A 188
 None
 0.89A 2cc8A-3ks7A:
undetectable		 2cc8A-3ks7A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 PHE A 154
VAL A  89
TRP A 188
 None
 0.89A 2ccbA-3ks7A:
undetectable		 2ccbA-3ks7A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 TYR A 204
TYR A  62
TYR A  53
ASN A 114
 None
 1.23A 2g72A-3ks7A:
undetectable		 2g72A-3ks7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 ARG A 174
ASP A  96
THR A 213
ASP A 210
 None
CL  A  12 ( 4.7A)
CL  A  12 ( 4.6A)
None
 1.29A 2okcB-3ks7A:
undetectable		 2okcB-3ks7A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 GLU A 373
TYR A 280
PHE A 311
PRO A 313
 EDO  A 420 ( 3.5A)
None
EDO  A 418 ( 4.4A)
EDO  A 420 (-4.5A)
 1.13A 2vmyA-3ks7A:
undetectable		 2vmyA-3ks7A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 3 PHE A 154
VAL A  89
TRP A 188
 None
 0.90A 2vx9A-3ks7A:
undetectable		 2vx9A-3ks7A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		3 / 4 SER A 164
GLY A 367
GLU A 293
 None
 0.56A 3raeA-3ks7A:
undetectable
3raeC-3ks7A:
undetectable		 3raeA-3ks7A:
23.06
3raeC-3ks7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 7 ASN A 245
GLY A 138
ILE A 118
LEU A 115
 None
 0.71A 4ejjD-3ks7A:
undetectable		 4ejjD-3ks7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 TYR A 163
ILE A 160
ASN A  94
TYR A 217
 None
 0.97A 4jtpA-3ks7A:
undetectable		 4jtpA-3ks7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 ILE A 300
PHE A 311
PHE A 258
THR A 246
 None
EDO  A 418 ( 4.4A)
None
None
 1.26A 5g08A-3ks7A:
undetectable		 5g08A-3ks7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 ALA A 409
VAL A 407
PHE A 387
ILE A 391
 None
 0.99A 5of1A-3ks7A:
2.2		 5of1A-3ks7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 5 ALA A 409
VAL A 407
PHE A 387
ILE A 391
 None
 0.95A 5of1B-3ks7A:
2.3		 5of1B-3ks7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		4 / 6 ASN A 185
ALA A  92
PRO A 157
VAL A 186
 None
 1.17A 5umd2-3ks7A:
undetectable
5umdF-3ks7A:
undetectable		 5umd2-3ks7A:
13.73
5umdF-3ks7A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 3ks7 PUTATIVE PUTATIVE
PNGASE F
(Bacteroides
fragilis) 		5 / 11 VAL A 106
LYS A 109
SER A 110
ALA A 203
LEU A 199
 None
 1.25A 5x6yC-3ks7A:
undetectable		 5x6yC-3ks7A:
21.29