SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 8 ILE A 342
VAL A 415
GLY A 363
LEU A 365
 None
 0.86A 1dzmA-3kscA:
undetectable		 1dzmA-3kscA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 12 THR A 401
ASP A 404
GLY A 405
TYR A 432
ALA A 434
 None
 1.18A 1oltA-3kscA:
undetectable		 1oltA-3kscA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 4 LEU A  15
PRO A  20
ILE A 382
LEU A 413
 None
 1.07A 1ya4C-3kscA:
undetectable		 1ya4C-3kscA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_M_RPTM8002_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 12 GLN A 172
GLN A 174
ARG A 158
ASN A 151
GLU A   9
 None
 1.22A 2a69M-3kscA:
0.3		 2a69M-3kscA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 7 ILE A 326
ARG A 323
ILE A  70
PHE A 435
 None
GOL  A 499 (-3.3A)
None
None
 1.05A 2q6hA-3kscA:
undetectable		 2q6hA-3kscA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 6 ILE A 326
ARG A 323
ILE A  70
PHE A 435
 None
GOL  A 499 (-3.3A)
None
None
 1.06A 2q72A-3kscA:
undetectable		 2q72A-3kscA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 7 ILE A 326
ARG A 323
ILE A  70
PHE A 435
 None
GOL  A 499 (-3.3A)
None
None
 1.04A 2qb4A-3kscA:
undetectable		 2qb4A-3kscA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 11 SER A 142
ILE A  70
PHE A 114
GLU A  32
LEU A  53
 None
 1.22A 2v0mA-3kscA:
undetectable		 2v0mA-3kscA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 11 SER A 142
ILE A  70
PHE A 114
GLU A  32
LEU A  53
 None
 1.18A 2v0mD-3kscA:
undetectable		 2v0mD-3kscA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 8 LEU A 407
ARG A 411
GLY A 410
ALA A 385
 None
 0.94A 2xfsA-3kscA:
undetectable		 2xfsA-3kscA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 8 LEU A 407
ARG A 411
GLY A 410
ALA A 385
 None
 0.91A 2xh9A-3kscA:
undetectable		 2xh9A-3kscA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 11 LEU A 143
THR A 437
GLY A  45
THR A 414
ILE A 382
 None
 1.33A 3bf1E-3kscA:
undetectable
3bf1F-3kscA:
undetectable		 3bf1E-3kscA:
18.76
3bf1F-3kscA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 6 HIS A 166
ARG A  60
ASN A 165
GLU A 218
 None
 1.36A 3galA-3kscA:
undetectable		 3galA-3kscA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 6 HIS A 166
ARG A  60
ASN A 165
GLU A 218
 None
 1.38A 3galB-3kscA:
undetectable		 3galB-3kscA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 8 PHE A  71
ILE A 119
PHE A 435
ALA A 434
 None
 0.89A 3me6B-3kscA:
undetectable		 3me6B-3kscA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 11 ASP A 118
ASN A 325
LEU A 324
VAL A 345
ALA A 360
 None
None
GOL  A 499 ( 4.9A)
None
None
 1.27A 3n23C-3kscA:
undetectable		 3n23C-3kscA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 3ksc LEGA CLASS
(Pisum
sativum) 		3 / 3 THR A 437
ASN A 380
SER A 381
 None
 0.74A 4tvtA-3kscA:
undetectable		 4tvtA-3kscA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3ksc LEGA CLASS
(Pisum
sativum) 		4 / 6 LEU A  48
ASP A  21
GLU A  32
ILE A 383
 None
 1.09A 4xi3C-3kscA:
undetectable		 4xi3C-3kscA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3ksc LEGA CLASS
(Pisum
sativum) 		3 / 3 LEU A 199
ARG A 207
ARG A 216
 None
None
SO4  A 498 ( 4.8A)
 0.93A 4yiaB-3kscA:
undetectable		 4yiaB-3kscA:
5.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ksc LEGA CLASS
(Pisum
sativum) 		5 / 12 SER A 431
GLY A 327
ASP A 349
VAL A 345
THR A 346
 SO4  A 497 ( 4.1A)
SO4  A 497 ( 4.8A)
None
None
None
 1.16A 5kpcB-3kscA:
undetectable		 5kpcB-3kscA:
19.44