SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ksg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A  57
LEU A  52
ARG A  85
 None
 0.76A 3hcnB-3ksgA:
undetectable		 3hcnB-3ksgA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3ksg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 PHE A  96
VAL A  90
GLU A 109
 None
None
SME  A6888 (-2.8A)
 0.78A 4fvqA-3ksgA:
undetectable		 4fvqA-3ksgA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3ksg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A  81
GLY A 122
GLY A  74
ILE A 120
ILE A  71
 None
None
None
None
SME  A6888 ( 4.2A)
 0.95A 4q5mA-3ksgA:
undetectable		 4q5mA-3ksgA:
23.19