SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 9 PHE A 187
THR A 231
LEU A 229
GLY A 254
THR A 159
 None
 1.25A 1dz8A-3ksmA:
undetectable		 1dz8A-3ksmA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 9 PHE A 187
THR A 231
LEU A 229
GLY A 254
THR A 159
 None
 1.31A 1dz8B-3ksmA:
undetectable		 1dz8B-3ksmA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 9 PHE A 187
THR A 231
LEU A 229
GLY A 254
THR A 159
 None
 1.30A 1dz9B-3ksmA:
undetectable		 1dz9B-3ksmA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 8 LEU A 171
ARG A 183
PHE A 187
GLY A 149
 None
BDR  A   1 (-3.2A)
None
None
 0.91A 1fapB-3ksmA:
undetectable		 1fapB-3ksmA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		3 / 3 ASN A 275
PHE A 230
VAL A 277
 None
 0.85A 1kijA-3ksmA:
undetectable		 1kijA-3ksmA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		3 / 3 LEU A 170
PHE A 187
ARG A 166
 None
 0.82A 1xdkB-3ksmA:
undetectable		 1xdkB-3ksmA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		3 / 3 LEU A 170
PHE A 187
ARG A 166
 None
 0.82A 1xdkF-3ksmA:
undetectable		 1xdkF-3ksmA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		3 / 3 SER A 114
VAL A  44
LEU A 103
 None
 0.58A 1yajG-3ksmA:
undetectable		 1yajG-3ksmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 11 PHE A 187
THR A 231
LEU A 229
GLY A 254
THR A 159
 None
 1.26A 2a1nA-3ksmA:
undetectable		 2a1nA-3ksmA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 8 SER A  49
ASN A  50
ASP A 207
ARG A 174
 None
BDR  A   1 ( 4.3A)
None
None
 1.12A 2v57A-3ksmA:
undetectable		 2v57A-3ksmA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 8 SER A  49
ASN A  50
ASP A 207
ARG A 174
 None
BDR  A   1 ( 4.3A)
None
None
 1.12A 2v57C-3ksmA:
undetectable		 2v57C-3ksmA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 5 VAL A 277
VAL A 278
THR A 231
ARG A 310
 None
 1.05A 3bjwA-3ksmA:
0.3		 3bjwA-3ksmA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 5 VAL A 277
VAL A 278
THR A 231
ARG A 310
 None
 1.07A 3bjwC-3ksmA:
0.3		 3bjwC-3ksmA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 4 VAL A 190
PHE A 187
PHE A 258
VAL A 309
 None
 1.21A 3rv5C-3ksmA:
undetectable
3rv5D-3ksmA:
undetectable		 3rv5C-3ksmA:
14.50
3rv5D-3ksmA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 9 ALA A 104
GLN A  61
LEU A  71
LEU A  45
LEU A  43
 None
 1.34A 4x30A-3ksmA:
undetectable		 4x30A-3ksmA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		5 / 12 ALA A 267
LEU A 241
PHE A 187
LEU A 160
PHE A 253
 None
 1.21A 5eshA-3ksmA:
undetectable		 5eshA-3ksmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		3 / 3 PRO A 232
ARG A 183
GLU A 184
 None
BDR  A   1 (-3.2A)
None
 0.82A 5j6hA-3ksmA:
undetectable		 5j6hA-3ksmA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 5 ASN A 106
ASP A  79
ASN A  50
ASP A 259
 None
None
BDR  A   1 ( 4.3A)
BDR  A   1 (-2.7A)
 1.30A 5vooA-3ksmA:
2.9		 5vooA-3ksmA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 5 ASN A 106
ASP A  79
ASN A  50
ASP A 259
 None
None
BDR  A   1 ( 4.3A)
BDR  A   1 (-2.7A)
 1.31A 5vooC-3ksmA:
undetectable		 5vooC-3ksmA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 5 ASN A 106
ASP A  79
ASN A  50
ASP A 259
 None
None
BDR  A   1 ( 4.3A)
BDR  A   1 (-2.7A)
 1.30A 5vooE-3ksmA:
undetectable		 5vooE-3ksmA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 8 ILE A 244
PHE A 253
PRO A 232
THR A 231
 None
 1.01A 5x23A-3ksmA:
undetectable		 5x23A-3ksmA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3ksm ABC-TYPE SUGAR
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT
(Hahella
chejuensis) 		4 / 8 THR A 143
THR A 307
TYR A 283
PRO A 105
 None
 1.26A 5x2sI-3ksmA:
undetectable
5x2sJ-3ksmA:
undetectable
5x2sK-3ksmA:
undetectable		 5x2sI-3ksmA:
18.84
5x2sJ-3ksmA:
22.02
5x2sK-3ksmA:
18.84