SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		4 / 4 GLY A  35
SER A 108
ILE A 188
HIS A 217
 None
PO4  A 290 ( 4.3A)
PO4  A 290 (-4.9A)
None
 1.30A 1yajJ-3ksrA:
3.9		 1yajJ-3ksrA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 12 GLY A 111
ALA A 132
LEU A 133
THR A 118
LEU A 126
 None
PO4  A 290 ( 3.8A)
None
None
None
 0.96A 2nyuB-3ksrA:
4.2		 2nyuB-3ksrA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 11 VAL A  51
LEU A  53
GLY A  54
PRO A  28
SER A 101
 None
 1.22A 3bjwE-3ksrA:
0.9		 3bjwE-3ksrA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 VAL A 104
LEU A  62
TYR A  88
GLY A 106
GLY A 110
 None
 1.08A 3ls4H-3ksrA:
undetectable		 3ls4H-3ksrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 VAL A 104
VAL A  33
LEU A  62
TYR A  88
GLY A 106
 None
 1.21A 3ls4H-3ksrA:
undetectable		 3ls4H-3ksrA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		4 / 7 VAL A 193
TYR A 197
LEU A 128
ASN A 147
 None
None
None
PO4  A 290 (-3.0A)
 0.80A 4e1gB-3ksrA:
undetectable		 4e1gB-3ksrA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 12 GLY A 110
LEU A 128
SER A 130
VAL A  33
VAL A 104
 None
 1.06A 5dpdA-3ksrA:
undetectable		 5dpdA-3ksrA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 12 VAL A 189
LEU A  62
ALA A 132
ARG A  72
LEU A 146
 None
None
PO4  A 290 ( 3.8A)
None
None
 1.23A 5syfB-3ksrA:
5.4		 5syfB-3ksrA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 LEU A 128
ILE A  84
LEU A  81
LEU A 166
ALA A 167
 None
 1.13A 5y7pB-3ksrA:
undetectable		 5y7pB-3ksrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 LEU A 128
ILE A  84
LEU A  81
LEU A 166
ALA A 167
 None
 1.14A 5y7pD-3ksrA:
undetectable		 5y7pD-3ksrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 LEU A 128
ILE A  84
LEU A  81
LEU A 166
ALA A 167
 None
 1.16A 5y7pH-3ksrA:
undetectable		 5y7pH-3ksrA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 ALA A  47
HIS A  42
LEU A 232
VAL A 105
GLY A 106
 None
 1.07A 5zbdA-3ksrA:
undetectable		 5zbdA-3ksrA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		5 / 10 ALA A  47
HIS A  42
LEU A 232
VAL A 105
GLY A 106
 None
 1.10A 5zbdB-3ksrA:
undetectable		 5zbdB-3ksrA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		3 / 3 LEU A  53
ASP A  98
ILE A 102
 None
 0.53A 6dh0B-3ksrA:
undetectable		 6dh0B-3ksrA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3ksr PUTATIVE SERINE
HYDROLASE
(Xanthomonas
campestris) 		3 / 3 ASP A 149
LEU A 152
ARG A 157
 None
 0.85A 7dfrA-3ksrA:
undetectable		 7dfrA-3ksrA:
20.56