SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RI4_A_SAMA299_0 (MRNA CAPPING ENZYME)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	5 / 12	GLY A 139 ILE A 92 ALA A 93 TYR A 4 GLN A 181	None	1.21A	1ri4A-3ksuA: 7.2	1ri4A-3ksuA: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJ3_B_GBNB914_1 (BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	5 / 10	GLY A 16 GLY A 22 THR A 25 ALA A 26 ALA A 23	None	1.13A	2ej3B-3ksuA: undetectable	2ej3B-3ksuA: 22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BGD_B_PM6B302_1 (THIOPURINE S-METHYLTRANSFERASE)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	4 / 7	THR A 25 LEU A 56 LEU A 38 LEU A 36	None	0.76A	3bgdB-3ksuA: 6.9	3bgdB-3ksuA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILT_H_TRUH800_1 (GLUTAMATE RECEPTOR 2)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	3 / 3	ILE A 128 SER A 174 SER A 183	None	0.60A	3iltH-3ksuA: undetectable	3iltH-3ksuA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LB3_B_4CHB192_0 (DEHALOPEROXIDASE A)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	4 / 6	PHE A 80 PHE A 127 HIS A 39 VAL A 37	None	1.06A	3lb3B-3ksuA: undetectable	3lb3B-3ksuA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3P_A_ACTA1223_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	4 / 5	THR A 48 LEU A 52 GLU A 55 LYS A 27	None	1.35A	4a3pA-3ksuA: undetectable	4a3pA-3ksuA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3A_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	5 / 12	GLY A 22 GLY A 16 ASN A 95 ALA A 15 PRO A 189	None	1.18A	6b3aA-3ksuA: 7.1	6b3aA-3ksuA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3B_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	3ksu	3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE (Oenococcus oeni)	5 / 12	GLY A 22 GLY A 16 ASN A 95 ALA A 15 PRO A 189	None	1.16A	6b3bA-3ksuA: 7.2	6b3bA-3ksuA: 16.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RI4_A_SAMA299_0","MRNA CAPPING ENZYME","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",5,"GLY A 139;ILE A  92;ALA A  93;TYR A   4;GLN A 181","None","1.21A","1ri4A-3ksuA:7.2","1ri4A-3ksuA:22.01"],["2EJ3_B_GBNB914_1","BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",5,"GLY A  16;GLY A  22;THR A  25;ALA A  26;ALA A  23","None","1.13A","2ej3B-3ksuA:undetectable","2ej3B-3ksuA:22.43"],["3BGD_B_PM6B302_1","THIOPURINE S-METHYLTRANSFERASE","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",4,"THR A  25;LEU A  56;LEU A  38;LEU A  36","None","0.76A","3bgdB-3ksuA:6.9","3bgdB-3ksuA:20.50"],["3ILT_H_TRUH800_1","GLUTAMATE RECEPTOR 2","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",3,"ILE A 128;SER A 174;SER A 183","None","0.60A","3iltH-3ksuA:undetectable","3iltH-3ksuA:22.82"],["3LB3_B_4CHB192_0","DEHALOPEROXIDASE A","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",4,"PHE A  80;PHE A 127;HIS A  39;VAL A  37","None","1.06A","3lb3B-3ksuA:undetectable","3lb3B-3ksuA:20.61"],["4A3P_A_ACTA1223_0","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",4,"THR A  48;LEU A  52;GLU A  55;LYS A  27","None","1.35A","4a3pA-3ksuA:undetectable","4a3pA-3ksuA:22.14"],["6B3A_A_SAMA701_0","APRA METHYLTRANSFERASE 1","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",5,"GLY A  22;GLY A  16;ASN A  95;ALA A  15;PRO A 189","None","1.18A","6b3aA-3ksuA:7.1","6b3aA-3ksuA:16.85"],["6B3B_A_SAMA701_0","APRA METHYLTRANSFERASE 1","3ksu","3-OXOACYL-ACYL CARRIER PROTEIN REDUCTASE","Oenococcus oeni",5,"GLY A  22;GLY A  16;ASN A  95;ALA A  15;PRO A 189","None","1.16A","6b3bA-3ksuA:7.2","6b3bA-3ksuA:16.85"]]