SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O1C_A_ADNA127_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	8 / 10	ILE A 6 PHE A 7 ILE A 10 ASP A 31 ILE A 32 LEU A 41 HIS A 100 HIS A 102	None	0.57A	3o1cA-3ksvA: 14.9	3o1cA-3ksvA: 27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O1X_A_ADNA1450_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	8 / 10	ILE A 6 PHE A 7 ILE A 10 ASP A 31 ILE A 32 LEU A 41 HIS A 100 HIS A 102	None	0.59A	3o1xA-3ksvA: 14.2	3o1xA-3ksvA: 27.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QGZ_A_ADNA127_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	8 / 10	ILE A 6 PHE A 7 ILE A 10 ASP A 31 ILE A 32 LEU A 41 HIS A 100 HIS A 102	None	0.52A	3qgzA-3ksvA: 14.4	3qgzA-3ksvA: 26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	4 / 8	ASN A 87 GLN A 94 HIS A 100 HIS A 102	None	0.25A	5km8A-3ksvA: 12.1 5km8B-3ksvA: 14.2	5km8A-3ksvA: 23.35 5km8B-3ksvA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM9_B_ADNB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	5 / 12	ILE A 6 PHE A 7 ILE A 10 ASP A 31 LEU A 41	None	0.61A	5km9B-3ksvA: 14.2	5km9B-3ksvA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM9_B_ADNB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	7 / 12	PHE A 7 ILE A 10 ASP A 31 LEU A 41 VAL A 96 HIS A 100 HIS A 102	None	0.45A	5km9B-3ksvA: 14.2	5km9B-3ksvA: 23.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5UVM_B_ADNB207_1 (HISTIDINE TRIAD (HIT) PROTEIN)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	6 / 12	ASP A 31 ILE A 32 ASN A 33 LEU A 41 HIS A 100 HIS A 102	None	1.05A	5uvmB-3ksvA: 15.8	5uvmB-3ksvA: 32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5UVM_B_ADNB207_1 (HISTIDINE TRIAD (HIT) PROTEIN)	3ksv	UNCHARACTERIZED PROTEIN (Leishmania major)	8 / 12	PHE A 7 ILE A 10 ASP A 31 ILE A 32 LEU A 41 VAL A 96 HIS A 100 HIS A 102	None	0.54A	5uvmB-3ksvA: 15.8	5uvmB-3ksvA: 32.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3O1C_A_ADNA127_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",8,"ILE A   6;PHE A   7;ILE A  10;ASP A  31;ILE A  32;LEU A  41;HIS A 100;HIS A 102","None","0.57A","3o1cA-3ksvA:14.9","3o1cA-3ksvA:27.45"],["3O1X_A_ADNA1450_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",8,"ILE A   6;PHE A   7;ILE A  10;ASP A  31;ILE A  32;LEU A  41;HIS A 100;HIS A 102","None","0.59A","3o1xA-3ksvA:14.2","3o1xA-3ksvA:27.45"],["3QGZ_A_ADNA127_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",8,"ILE A   6;PHE A   7;ILE A  10;ASP A  31;ILE A  32;LEU A  41;HIS A 100;HIS A 102","None","0.52A","3qgzA-3ksvA:14.4","3qgzA-3ksvA:26.80"],["5KM8_B_L8PB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL;HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",4,"ASN A  87;GLN A  94;HIS A 100;HIS A 102","None","0.25A","5km8A-3ksvA:12.1;5km8B-3ksvA:14.2","5km8A-3ksvA:23.35;5km8B-3ksvA:23.35"],["5KM9_B_ADNB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",5,"ILE A   6;PHE A   7;ILE A  10;ASP A  31;LEU A  41","None","0.61A","5km9B-3ksvA:14.2","5km9B-3ksvA:23.35"],["5KM9_B_ADNB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",7,"PHE A   7;ILE A  10;ASP A  31;LEU A  41;VAL A  96;HIS A 100;HIS A 102","None","0.45A","5km9B-3ksvA:14.2","5km9B-3ksvA:23.35"],["5UVM_B_ADNB207_1","HISTIDINE TRIAD (HIT) PROTEIN","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",6,"ASP A  31;ILE A  32;ASN A  33;LEU A  41;HIS A 100;HIS A 102","None","1.05A","5uvmB-3ksvA:15.8","5uvmB-3ksvA:32.30"],["5UVM_B_ADNB207_1","HISTIDINE TRIAD (HIT) PROTEIN","3ksv","UNCHARACTERIZED PROTEIN","Leishmania major",8,"PHE A   7;ILE A  10;ASP A  31;ILE A  32;LEU A  41;VAL A  96;HIS A 100;HIS A 102","None","0.54A","5uvmB-3ksvA:15.8","5uvmB-3ksvA:32.30"]]