SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ksx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 LEU A 100
GLY A  84
GLN A  36
LEU A  91
VAL A 276
 None
None
MPO  A 325 (-3.1A)
None
None
 1.12A 2w8yA-3ksxA:
undetectable		 2w8yA-3ksxA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 LEU A 146
ALA A 170
ALA A  67
VAL A 117
ILE A 134
 None
None
MPO  A 325 ( 3.7A)
None
None
 1.09A 3czhB-3ksxA:
undetectable		 3czhB-3ksxA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 11 ALA A  45
LEU A 235
GLY A  83
VAL A  39
GLY A  34
 None
None
None
MPO  A 325 ( 4.9A)
None
 1.13A 3zosA-3ksxA:
undetectable
3zosB-3ksxA:
1.1		 3zosA-3ksxA:
22.79
3zosB-3ksxA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 8 HIS A 143
GLY A 139
ALA A 142
SER A 140
GLU A 113
 None
None
None
MPO  A 325 (-4.5A)
MPO  A 325 (-3.5A)
 1.36A 4bjcA-3ksxA:
undetectable		 4bjcA-3ksxA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		4 / 5 LEU A  31
LEU A  82
MET A 232
TRP A 311
 None
 1.38A 4do3A-3ksxA:
1.4		 4do3A-3ksxA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 ALA A 296
ILE A  88
LEU A  91
HIS A 143
LEU A 147
 None
 1.24A 4j24D-3ksxA:
undetectable		 4j24D-3ksxA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 LEU A  50
GLN A 237
LEU A 241
ARG A 244
ILE A  60
 None
 1.41A 4p6xI-3ksxA:
undetectable		 4p6xI-3ksxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 VAL A 310
LEU A  72
ALA A  93
LEU A  91
ALA A  85
 None
None
None
None
MPO  A 325 (-3.7A)
 0.96A 4x1kA-3ksxA:
undetectable
4x1kB-3ksxA:
undetectable		 4x1kA-3ksxA:
24.51
4x1kB-3ksxA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 9 ALA A 238
LEU A 268
LEU A  44
LEU A 242
ARG A 246
 None
 1.32A 4x30A-3ksxA:
undetectable		 4x30A-3ksxA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 GLY A 240
ALA A 247
ILE A 250
LEU A 268
ALA A 274
 None
 1.10A 5bw4B-3ksxA:
undetectable		 5bw4B-3ksxA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 LEU A 299
PHE A 294
LEU A 209
LEU A 207
ALA A 183
 None
 1.32A 5ieoA-3ksxA:
undetectable		 5ieoA-3ksxA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		5 / 12 ILE A  80
PHE A 227
GLY A  84
LEU A 235
PHE A  55
 None
 1.24A 5v5zA-3ksxA:
undetectable		 5v5zA-3ksxA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3ksx NITRATE TRANSPORT
PROTEIN
(Xanthomonas
citri) 		3 / 3 VAL A 304
ALA A 291
GLN A  94
 None
 0.57A 6gb9A-3ksxA:
undetectable		 6gb9A-3ksxA:
22.87