SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ktc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 1.02A 1fbyA-3ktcA:
undetectable		 1fbyA-3ktcA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 1.02A 1fbyB-3ktcA:
undetectable		 1fbyB-3ktcA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.11A 1p7lC-3ktcA:
undetectable		 1p7lC-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.10A 1p7lD-3ktcA:
undetectable		 1p7lD-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.11A 1rg9A-3ktcA:
undetectable		 1rg9A-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.13A 1rg9B-3ktcA:
undetectable		 1rg9B-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.13A 1rg9C-3ktcA:
undetectable		 1rg9C-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.12A 1rg9D-3ktcA:
undetectable		 1rg9D-3ktcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 0.94A 1xdkA-3ktcA:
undetectable		 1xdkA-3ktcA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 0.94A 1xdkE-3ktcA:
undetectable		 1xdkE-3ktcA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 10 TRP A  14
TRP A 126
GLU A 166
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.51A 1xidA-3ktcA:
36.4		 1xidA-3ktcA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		7 / 12 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.56A 1xihA-3ktcA:
36.4		 1xihA-3ktcA:
27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 1.00A 1xiuA-3ktcA:
undetectable		 1xiuA-3ktcA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 ASN A 158
ALA A 104
ILE A  83
PHE A 163
ILE A 165
 None
 1.25A 2h42A-3ktcA:
undetectable		 2h42A-3ktcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 324
GLN A 271
ILE A 251
PHE A 252
 None
 0.96A 2jn3A-3ktcA:
undetectable		 2jn3A-3ktcA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.32A 2xinA-3ktcA:
35.8		 2xinA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.07A 2xinA-3ktcA:
35.8		 2xinA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.75A 2xinA-3ktcA:
35.8		 2xinA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.06A 2xinB-3ktcA:
35.8		 2xinB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		7 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
ASP A 229
ASP A 238
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
 0.92A 2xinB-3ktcA:
35.8		 2xinB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.53A 2xinB-3ktcA:
35.8		 2xinB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.05A 2xinC-3ktcA:
35.7		 2xinC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.84A 2xinC-3ktcA:
35.7		 2xinC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.53A 2xinC-3ktcA:
35.7		 2xinC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.09A 2xinD-3ktcA:
35.8		 2xinD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.88A 2xinD-3ktcA:
35.8		 2xinD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.52A 2xinD-3ktcA:
35.8		 2xinD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 6 ASP A  51
HIS A 204
ASP A 238
ASP A 240
 None
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 333 (-2.5A)
 1.17A 3c0zC-3ktcA:
undetectable		 3c0zC-3ktcA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A  13
ASP A  51
VAL A  50
ILE A  77
GLY A  78
 None
 1.08A 3hgiA-3ktcA:
undetectable		 3hgiA-3ktcA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 289
SER A 285
PHE A 288
ILE A 251
ASP A 229
 None
None
None
None
FE  A 334 (-3.1A)
 1.26A 3ko0A-3ktcA:
undetectable
3ko0B-3ktcA:
undetectable
3ko0C-3ktcA:
undetectable
3ko0D-3ktcA:
undetectable		 3ko0A-3ktcA:
16.22
3ko0B-3ktcA:
16.22
3ko0C-3ktcA:
16.22
3ko0D-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 LEU A 289
SER A 285
PHE A 288
ILE A 251
ASP A 229
 None
None
None
None
FE  A 334 (-3.1A)
 1.26A 3ko0A-3ktcA:
undetectable
3ko0B-3ktcA:
undetectable
3ko0C-3ktcA:
undetectable
3ko0D-3ktcA:
undetectable		 3ko0A-3ktcA:
16.22
3ko0B-3ktcA:
16.22
3ko0C-3ktcA:
16.22
3ko0D-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 ASP A 229
LEU A 289
SER A 285
PHE A 288
ILE A 251
 FE  A 334 (-3.1A)
None
None
None
None
 1.25A 3ko0E-3ktcA:
undetectable
3ko0F-3ktcA:
undetectable
3ko0G-3ktcA:
undetectable
3ko0H-3ktcA:
undetectable		 3ko0E-3ktcA:
16.22
3ko0F-3ktcA:
16.22
3ko0G-3ktcA:
16.22
3ko0H-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ASP A 229
LEU A 289
SER A 285
PHE A 288
ILE A 251
 FE  A 334 (-3.1A)
None
None
None
None
 1.21A 3ko0G-3ktcA:
undetectable
3ko0H-3ktcA:
undetectable
3ko0I-3ktcA:
undetectable
3ko0J-3ktcA:
undetectable		 3ko0G-3ktcA:
16.22
3ko0H-3ktcA:
16.22
3ko0I-3ktcA:
16.22
3ko0J-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 289
SER A 285
PHE A 288
ILE A 251
ASP A 229
 None
None
None
None
FE  A 334 (-3.1A)
 1.23A 3ko0K-3ktcA:
undetectable
3ko0L-3ktcA:
undetectable
3ko0S-3ktcA:
undetectable
3ko0T-3ktcA:
undetectable		 3ko0K-3ktcA:
16.22
3ko0L-3ktcA:
16.22
3ko0S-3ktcA:
16.22
3ko0T-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ASP A 229
LEU A 289
SER A 285
PHE A 288
ILE A 251
 FE  A 334 (-3.1A)
None
None
None
None
 1.25A 3ko0K-3ktcA:
undetectable
3ko0L-3ktcA:
undetectable
3ko0M-3ktcA:
undetectable
3ko0N-3ktcA:
undetectable		 3ko0K-3ktcA:
16.22
3ko0L-3ktcA:
16.22
3ko0M-3ktcA:
16.22
3ko0N-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 ASP A 229
LEU A 289
SER A 285
PHE A 288
ILE A 251
 FE  A 334 (-3.1A)
None
None
None
None
 1.27A 3ko0K-3ktcA:
undetectable
3ko0L-3ktcA:
undetectable
3ko0M-3ktcA:
undetectable
3ko0N-3ktcA:
undetectable		 3ko0K-3ktcA:
16.22
3ko0L-3ktcA:
16.22
3ko0M-3ktcA:
16.22
3ko0N-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 LEU A 289
SER A 285
PHE A 288
ILE A 251
ASP A 229
 None
None
None
None
FE  A 334 (-3.1A)
 1.32A 3ko0O-3ktcA:
undetectable
3ko0P-3ktcA:
undetectable
3ko0Q-3ktcA:
undetectable
3ko0R-3ktcA:
undetectable		 3ko0O-3ktcA:
16.22
3ko0P-3ktcA:
16.22
3ko0Q-3ktcA:
16.22
3ko0R-3ktcA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 VAL A 198
PHE A 254
PHE A 255
GLY A 265
ILE A  77
 None
None
None
EDO  A 341 (-3.3A)
None
 1.39A 3owxA-3ktcA:
undetectable
3owxB-3ktcA:
undetectable		 3owxA-3ktcA:
22.83
3owxB-3ktcA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 9 ALA A  92
PHE A  93
ILE A 165
ASP A 130
GLU A 166
 None
None
None
None
FE  A 334 (-2.6A)
 1.20A 3rukC-3ktcA:
undetectable		 3rukC-3ktcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 GLY A 209
ILE A 251
GLY A 203
ALA A 205
ALA A 213
 None
 1.09A 3sudB-3ktcA:
undetectable		 3sudB-3ktcA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 7 ASN A 195
ALA A 155
ALA A 112
ARG A 116
 None
 1.08A 3twpA-3ktcA:
undetectable		 3twpA-3ktcA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 7 ASN A 195
ALA A 155
ALA A 112
ARG A 116
 None
 1.11A 3twpB-3ktcA:
undetectable		 3twpB-3ktcA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 7 ASN A 195
ALA A 155
ALA A 112
ARG A 116
 None
 1.09A 3twpC-3ktcA:
undetectable		 3twpC-3ktcA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.58A 3ximA-3ktcA:
35.8		 3ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.28A 3ximB-3ktcA:
35.8		 3ximB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.09A 3ximB-3ktcA:
35.8		 3ximB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.60A 3ximB-3ktcA:
35.8		 3ximB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.29A 3ximC-3ktcA:
35.8		 3ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.11A 3ximC-3ktcA:
35.8		 3ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.59A 3ximC-3ktcA:
35.8		 3ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.13A 3ximD-3ktcA:
35.8		 3ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.55A 3ximD-3ktcA:
35.8		 3ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 6 PHE A 254
ALA A 216
GLY A 227
LEU A 200
VAL A 198
 None
None
EDO  A 341 (-3.6A)
None
None
 1.38A 4dubB-3ktcA:
undetectable		 4dubB-3ktcA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		7 / 12 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 238
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
 0.63A 4dvoA-3ktcA:
36.6		 4dvoA-3ktcA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		7 / 12 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.55A 4xiaA-3ktcA:
36.0		 4xiaA-3ktcA:
26.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.10A 4xiaB-3ktcA:
36.1		 4xiaB-3ktcA:
26.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.55A 4xiaB-3ktcA:
36.1		 4xiaB-3ktcA:
26.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		3 / 3 LEU A 193
VAL A 148
ASP A 149
 None
 0.35A 4y8wC-3ktcA:
undetectable		 4y8wC-3ktcA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 11 VAL A 198
PHE A 254
PHE A 255
GLY A 265
ILE A  77
 None
None
None
EDO  A 341 (-3.3A)
None
 1.36A 4zvmA-3ktcA:
undetectable
4zvmB-3ktcA:
undetectable		 4zvmA-3ktcA:
23.01
4zvmB-3ktcA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 5 GLN A 305
ILE A 301
ILE A 319
TYR A 256
 UNL  A 338 ( 3.8A)
UNL  A 338 ( 3.7A)
None
None
 0.96A 5dnuA-3ktcA:
undetectable		 5dnuA-3ktcA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 5 GLN A 305
ILE A 301
ILE A 319
TYR A 256
 UNL  A 338 ( 3.8A)
UNL  A 338 ( 3.7A)
None
None
 1.00A 5dnvA-3ktcA:
undetectable		 5dnvA-3ktcA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 12 VAL A  50
LEU A  47
LEU A  13
GLY A  73
ALA A  72
LEU A  69
 None
 1.47A 5jvzA-3ktcA:
undetectable		 5jvzA-3ktcA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 12 VAL A  50
LEU A  47
LEU A  13
GLY A  73
ALA A  72
LEU A  69
 None
 1.48A 5jvzB-3ktcA:
undetectable		 5jvzB-3ktcA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 TRP A 126
GLU A 166
ASP A 240
TRP A  14
 UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-2.5A)
UNL  A 337 ( 3.9A)
 1.00A 5kf8A-3ktcA:
1.0		 5kf8A-3ktcA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGJ_A_X6XA402_1
(PREDICTED
ACETYLTRANSFERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 5 TRP A 126
GLU A 166
ASP A 240
TRP A  14
 UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-2.5A)
UNL  A 337 ( 3.9A)
 1.03A 5kgjA-3ktcA:
1.0		 5kgjA-3ktcA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 TRP A 126
GLU A 166
ASP A 240
TRP A  14
 UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-2.5A)
UNL  A 337 ( 3.9A)
 1.01A 5kgpA-3ktcA:
undetectable		 5kgpA-3ktcA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 TRP A 126
GLU A 166
ASP A 240
TRP A  14
 UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-2.5A)
UNL  A 337 ( 3.9A)
 1.03A 5kgpB-3ktcA:
undetectable		 5kgpB-3ktcA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 9 TRP A  14
TRP A 126
GLU A 166
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.52A 5nhaA-3ktcA:
32.8		 5nhaA-3ktcA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 9 TRP A  14
TRP A 126
GLU A 166
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.52A 5nhaB-3ktcA:
32.8		 5nhaB-3ktcA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 9 TRP A  14
TRP A 126
GLU A 166
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.53A 5nhaC-3ktcA:
32.7		 5nhaC-3ktcA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		6 / 9 TRP A  14
TRP A 126
GLU A 166
HIS A 204
ASP A 229
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 334 (-2.9A)
 0.53A 5nhaD-3ktcA:
32.7		 5nhaD-3ktcA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		4 / 8 ASP A 201
LYS A 168
THR A  80
ASP A 240
 FE  A 334 ( 3.2A)
UNL  A 337 ( 2.9A)
UNL  A 337 ( 3.8A)
FE  A 333 (-2.5A)
 1.09A 5t8sB-3ktcA:
undetectable		 5t8sB-3ktcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 MET A 228
ALA A 216
PHE A 255
LEU A 269
LEU A 289
 None
 1.17A 5tudA-3ktcA:
undetectable		 5tudA-3ktcA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.31A 5ximA-3ktcA:
35.8		 5ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 240
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-2.5A)
FE  A 334 (-3.1A)
 1.36A 5ximA-3ktcA:
35.8		 5ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.10A 5ximA-3ktcA:
35.8		 5ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.61A 5ximA-3ktcA:
35.8		 5ximA-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		8 / 12 TRP A  14
THR A  80
TRP A 126
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.69A 5ximB-3ktcA:
35.7		 5ximB-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.26A 5ximC-3ktcA:
35.7		 5ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 240
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-2.5A)
FE  A 334 (-3.1A)
 1.29A 5ximC-3ktcA:
35.7		 5ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.10A 5ximC-3ktcA:
35.7		 5ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.66A 5ximC-3ktcA:
35.7		 5ximC-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 238
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-1.9A)
FE  A 334 (-3.1A)
 1.28A 5ximD-3ktcA:
35.7		 5ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
GLU A 166
HIS A 204
ASP A 240
ASP A 229
 UNL  A 337 ( 3.8A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 333 (-2.5A)
FE  A 334 (-3.1A)
 1.35A 5ximD-3ktcA:
35.7		 5ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 THR A  80
TRP A 126
GLU A 166
HIS A 204
ASP A 270
 UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
FE  A 333 (-3.3A)
FE  A 334 (-2.9A)
 1.11A 5ximD-3ktcA:
35.7		 5ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		9 / 12 TRP A  14
THR A  80
TRP A 126
GLU A 166
LYS A 168
HIS A 204
ASP A 229
ASP A 238
ASP A 270
 UNL  A 337 ( 3.9A)
UNL  A 337 ( 3.8A)
UNL  A 337 ( 3.7A)
FE  A 334 (-2.6A)
UNL  A 337 ( 2.9A)
FE  A 333 (-3.3A)
FE  A 334 (-3.1A)
FE  A 333 (-1.9A)
FE  A 334 (-2.9A)
 0.63A 5ximD-3ktcA:
35.7		 5ximD-3ktcA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 292
ALA A 295
LEU A 324
ALA A 323
VAL A 230
 None
 0.95A 5z12B-3ktcA:
undetectable		 5z12B-3ktcA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3ktc XYLOSE ISOMERASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 219
LEU A 258
PHE A 254
ASP A 229
ILE A 165
 None
None
None
FE  A 334 (-3.1A)
None
 1.33A 6dwnB-3ktcA:
undetectable		 6dwnB-3ktcA:
13.77