SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ktd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 140
LEU A  17
LEU A 239
GLY A 127
 None
 1.04A 1a4lC-3ktdA:
undetectable		 1a4lC-3ktdA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A  83
VAL A  99
ILE A  18
GLY A  16
PRO A  76
 None
 1.19A 1d4sA-3ktdA:
undetectable		 1d4sA-3ktdA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		3 / 3 GLU A 205
THR A 206
LEU A 255
 None
 0.70A 1v8bC-3ktdA:
3.9		 1v8bC-3ktdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 ALA A 242
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 1.09A 2f16H-3ktdA:
undetectable
2f16I-3ktdA:
undetectable		 2f16H-3ktdA:
21.78
2f16I-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.87A 2f16H-3ktdA:
undetectable
2f16I-3ktdA:
undetectable		 2f16H-3ktdA:
21.78
2f16I-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 ALA A 242
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 1.09A 2f16V-3ktdA:
undetectable
2f16W-3ktdA:
undetectable		 2f16V-3ktdA:
21.78
2f16W-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.87A 2f16V-3ktdA:
undetectable
2f16W-3ktdA:
undetectable		 2f16V-3ktdA:
21.78
2f16W-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		3 / 3 LYS A 111
GLY A 187
PRO A 188
 None
 0.94A 2hreB-3ktdA:
undetectable		 2hreB-3ktdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A  70
VAL A  33
GLY A  19
ILE A  18
VAL A  10
 None
 1.04A 2nnpB-3ktdA:
undetectable		 2nnpB-3ktdA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 5 VAL A 171
VAL A 120
GLY A 121
TRP A 167
 None
 1.15A 2p2fA-3ktdA:
4.4		 2p2fA-3ktdA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 MET A  77
ILE A  80
ALA A 105
THR A 149
VAL A 170
 None
 1.38A 2rctA-3ktdA:
undetectable		 2rctA-3ktdA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A  20
ALA A 135
ALA A  46
ILE A  18
ALA A  74
 None
 1.10A 3jb1A-3ktdA:
3.8		 3jb1A-3ktdA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.87A 3mg0H-3ktdA:
undetectable
3mg0I-3ktdA:
undetectable		 3mg0H-3ktdA:
21.78
3mg0I-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 ALA A 242
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 1.11A 3mg0V-3ktdA:
undetectable
3mg0W-3ktdA:
undetectable		 3mg0V-3ktdA:
21.78
3mg0W-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.91A 3mg0V-3ktdA:
undetectable
3mg0W-3ktdA:
undetectable		 3mg0V-3ktdA:
21.78
3mg0W-3ktdA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 10 LEU A  70
VAL A  33
GLY A  19
ILE A  18
VAL A  10
 None
 0.95A 3nu9B-3ktdA:
undetectable		 3nu9B-3ktdA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 8 THR A  60
LEU A  83
LEU A  13
GLY A  14
 None
 0.88A 4c9nA-3ktdA:
undetectable		 4c9nA-3ktdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  15
GLY A  14
VAL A  10
MET A 173
ILE A  80
 None
 1.40A 4oktA-3ktdA:
undetectable		 4oktA-3ktdA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.88A 4qvpH-3ktdA:
undetectable
4qvpI-3ktdA:
undetectable		 4qvpH-3ktdA:
21.71
4qvpI-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.89A 4qvpV-3ktdA:
undetectable
4qvpW-3ktdA:
undetectable		 4qvpV-3ktdA:
21.71
4qvpW-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.90A 4qvvH-3ktdA:
undetectable		 4qvvH-3ktdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.90A 4qvvV-3ktdA:
undetectable		 4qvvV-3ktdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.91A 4qvyH-3ktdA:
undetectable		 4qvyH-3ktdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.90A 4qvyV-3ktdA:
undetectable
4qvyW-3ktdA:
undetectable		 4qvyV-3ktdA:
21.71
4qvyW-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.90A 4qw0H-3ktdA:
undetectable
4qw0I-3ktdA:
undetectable		 4qw0H-3ktdA:
21.71
4qw0I-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.90A 4qw0V-3ktdA:
undetectable
4qw0W-3ktdA:
undetectable		 4qw0V-3ktdA:
21.71
4qw0W-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.91A 4qw1H-3ktdA:
undetectable
4qw1I-3ktdA:
undetectable		 4qw1H-3ktdA:
21.71
4qw1I-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.91A 4qw1V-3ktdA:
undetectable
4qw1W-3ktdA:
undetectable		 4qw1V-3ktdA:
21.71
4qw1W-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 MET A  77
ILE A  80
ALA A 105
THR A 149
VAL A 170
 None
 1.31A 4qynA-3ktdA:
undetectable		 4qynA-3ktdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 122
PRO A 124
PHE A 141
ILE A  18
VAL A  72
 None
 1.05A 4yfbC-3ktdA:
undetectable		 4yfbC-3ktdA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 122
PRO A 124
PHE A 141
ILE A  18
VAL A  72
 None
 1.04A 4yfbF-3ktdA:
undetectable		 4yfbF-3ktdA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 122
PRO A 124
PHE A 141
ILE A  18
VAL A  72
 None
 1.04A 4yfbI-3ktdA:
undetectable		 4yfbI-3ktdA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 122
PRO A 124
PHE A 141
ILE A  18
VAL A  72
 None
 1.06A 4yfbL-3ktdA:
undetectable		 4yfbL-3ktdA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 6 ARG A 185
GLY A 187
THR A 332
GLU A 331
 None
 1.05A 5btcA-3ktdA:
undetectable
5btcC-3ktdA:
undetectable
5btcD-3ktdA:
undetectable		 5btcA-3ktdA:
25.00
5btcC-3ktdA:
25.00
5btcD-3ktdA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.87A 5bxnH-3ktdA:
undetectable
5bxnI-3ktdA:
undetectable		 5bxnH-3ktdA:
23.96
5bxnI-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.87A 5bxnV-3ktdA:
undetectable
5bxnW-3ktdA:
undetectable		 5bxnV-3ktdA:
23.96
5bxnW-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.89A 5cz7V-3ktdA:
undetectable
5cz7W-3ktdA:
undetectable		 5cz7V-3ktdA:
21.71
5cz7W-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.89A 5d0xV-3ktdA:
undetectable		 5d0xV-3ktdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 5 HIS A 198
HIS A 123
VAL A 102
ALA A 193
 None
 1.14A 5i3bB-3ktdA:
undetectable		 5i3bB-3ktdA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.88A 5l5fH-3ktdA:
undetectable
5l5fI-3ktdA:
undetectable		 5l5fH-3ktdA:
21.71
5l5fI-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.88A 5l5fV-3ktdA:
undetectable
5l5fW-3ktdA:
undetectable		 5l5fV-3ktdA:
21.71
5l5fW-3ktdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  70
THR A  97
VAL A 120
SER A 122
VAL A 181
 None
 1.48A 5v1tA-3ktdA:
undetectable		 5v1tA-3ktdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		4 / 9 VAL A  87
HIS A  90
VAL A  33
SER A  32
 None
 0.93A 6c2mD-3ktdA:
undetectable		 6c2mD-3ktdA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 10 MET A 137
SER A  21
GLY A  19
ALA A 129
GLY A 132
 None
 1.08A 6hqbA-3ktdA:
undetectable
6hqbJ-3ktdA:
undetectable		 6hqbA-3ktdA:
13.51
6hqbJ-3ktdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.93A 6hwdH-3ktdA:
undetectable
6hwdI-3ktdA:
undetectable		 6hwdH-3ktdA:
14.76
6hwdI-3ktdA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 11 SER A 101
ALA A 126
GLY A 127
THR A 128
ALA A 129
 None
 0.93A 6hwdV-3ktdA:
undetectable		 6hwdV-3ktdA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3ktd PREPHENATE
DEHYDROGENASE
(Corynebacterium
glutamicum) 		5 / 12 PHE A  51
GLY A  35
ASP A  25
ASN A  37
SER A  54
 None
 1.02A 6mhtA-3ktdA:
4.2		 6mhtA-3ktdA:
20.26