SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ktw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3ktw SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Sulfolobus
solfataricus) 		4 / 7 ARG A  28
ILE A  33
LEU A  42
THR A  82
 C  C 158 ( 3.2A)
None
None
None
 1.26A 3nxuA-3ktwA:
undetectable		 3nxuA-3ktwA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3ktw SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Sulfolobus
solfataricus) 		5 / 10 VAL A  73
TYR A  81
THR A  82
ILE A  85
ILE A  86
 None
 0.85A 3p4wD-3ktwA:
undetectable		 3p4wD-3ktwA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3ktw SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN
(Sulfolobus
solfataricus) 		5 / 10 VAL A  73
TYR A  81
THR A  82
ILE A  85
ILE A  86
 None
 0.85A 3p4wE-3ktwA:
undetectable		 3p4wE-3ktwA:
15.48