SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kty'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		4 / 6 ALA A 161
LEU A 160
ILE A 143
CYH A  97
 None
 1.02A 1sbrA-3ktyA:
undetectable
1sbrB-3ktyA:
undetectable		 1sbrA-3ktyA:
24.37
1sbrB-3ktyA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		7 / 12 GLY A 123
GLY A 128
ILE A 143
SER A 151
LEU A 152
VAL A 154
ALA A 157
 None
 0.96A 1v2xA-3ktyA:
17.7		 1v2xA-3ktyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 11 GLY A 123
GLY A 128
ILE A 143
LEU A 152
ALA A 157
 None
 0.86A 1x7pA-3ktyA:
18.5
1x7pB-3ktyA:
18.6		 1x7pA-3ktyA:
24.65
1x7pB-3ktyA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 10 GLY A 123
GLY A 128
ILE A 143
LEU A 152
ALA A 157
 None
 0.84A 1x7pA-3ktyA:
18.5
1x7pB-3ktyA:
18.6		 1x7pA-3ktyA:
24.65
1x7pB-3ktyA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.01A 2aylA-3ktyA:
undetectable		 2aylA-3ktyA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		6 / 11 GLY A 123
GLY A 128
ILE A 143
LEU A 152
VAL A 154
ALA A 157
 None
 0.83A 3dcmX-3ktyA:
16.1		 3dcmX-3ktyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 11 LEU A  85
GLY A 123
ILE A 143
SER A 151
VAL A 154
 None
 0.94A 3gyqB-3ktyA:
17.4		 3gyqB-3ktyA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.08A 3n8zB-3ktyA:
undetectable		 3n8zB-3ktyA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		8 / 12 ASN A  20
LEU A  85
GLY A 123
GLY A 128
ILE A 143
SER A 151
ASN A 153
VAL A 154
 None
 0.75A 3nk7A-3ktyA:
17.6		 3nk7A-3ktyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		7 / 12 ASN A  20
GLY A 123
GLY A 128
ILE A 143
SER A 151
LEU A 152
VAL A 154
 None
 0.84A 3nk7B-3ktyA:
17.6		 3nk7B-3ktyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		7 / 12 ASN A  20
LEU A  85
GLY A 123
GLY A 128
ILE A 143
SER A 151
VAL A 154
 None
 0.73A 3nk7B-3ktyA:
17.6		 3nk7B-3ktyA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.15A 3pghA-3ktyA:
undetectable		 3pghA-3ktyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.20A 4rrwB-3ktyA:
undetectable		 4rrwB-3ktyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.20A 4rrzB-3ktyA:
undetectable		 4rrzB-3ktyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 9 VAL A 118
LEU A  81
GLY A 104
ALA A 103
LEU A 165
 None
 1.10A 4rs0A-3ktyA:
undetectable		 4rs0A-3ktyA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 12 GLY A 123
GLY A 128
ILE A 143
LEU A 152
ALA A 157
 None
 0.77A 5l0zA-3ktyA:
18.7		 5l0zA-3ktyA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 10 GLY A 123
GLY A 128
ILE A 143
LEU A 152
ALA A 157
 None
 0.79A 5l0zB-3ktyA:
18.4		 5l0zB-3ktyA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 10 LEU A  85
GLY A 123
GLU A 125
GLY A 128
ALA A 157
 None
 0.94A 5o96C-3ktyA:
12.8
5o96D-3ktyA:
12.6		 5o96C-3ktyA:
21.07
5o96D-3ktyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		5 / 10 LEU A  85
GLY A 123
GLU A 125
GLY A 128
ALA A 157
 None
 0.91A 5o96E-3ktyA:
12.5
5o96F-3ktyA:
10.7		 5o96E-3ktyA:
21.07
5o96F-3ktyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3kty PROBABLE
METHYLTRANSFERASE
(Bordetella
pertussis) 		4 / 6 MET A  46
ALA A  25
LEU A  36
ALA A  66
 None
 1.02A 6fosB-3ktyA:
undetectable		 6fosB-3ktyA:
19.19