SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ku0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		4 / 8 SER A  34
ASN A  33
ILE A  37
GLY A 209
 None
 0.99A 1meiA-3ku0A:
undetectable		 1meiA-3ku0A:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		7 / 9 TYR A  74
PHE A  87
GLY A 111
TYR A 113
ILE A 161
GLU A 166
ARG A 169
 ADE  A 800 (-3.5A)
ADE  A 800 (-4.6A)
ADE  A 800 (-4.1A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.32A 1mrgA-3ku0A:
33.9		 1mrgA-3ku0A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		7 / 8 TYR A  74
GLY A 111
TYR A 113
ILE A 161
SER A 165
GLU A 166
ARG A 169
 ADE  A 800 (-3.5A)
ADE  A 800 (-4.1A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 3.7A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.25A 1mrjA-3ku0A:
33.7		 1mrjA-3ku0A:
37.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		5 / 12 ILE A 240
LYS A 197
GLY A 199
LEU A  39
ARG A 206
 None
 1.06A 3em0B-3ku0A:
undetectable		 3em0B-3ku0A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		5 / 12 LEU A 157
ILE A 161
ILE A  66
ALA A  67
ALA A  90
 None
ADE  A 800 (-4.0A)
None
None
None
 1.08A 4enhA-3ku0A:
undetectable		 4enhA-3ku0A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		4 / 5 LEU A 157
VAL A  54
VAL A  73
TYR A  78
 None
 1.01A 4r7iA-3ku0A:
undetectable		 4r7iA-3ku0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		3 / 3 GLU A 166
ALA A 167
PHE A 170
 ADE  A 800 ( 4.5A)
None
None
 0.65A 4v1fA-3ku0A:
undetectable		 4v1fA-3ku0A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		3 / 3 GLU A 166
ALA A 167
PHE A 170
 ADE  A 800 ( 4.5A)
None
None
 0.62A 4v1fC-3ku0A:
undetectable		 4v1fC-3ku0A:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		6 / 9 PHE A  87
GLY A 111
TYR A 113
ILE A 161
GLU A 166
ARG A 169
 ADE  A 800 (-4.6A)
ADE  A 800 (-4.1A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.23A 4yp2B-3ku0A:
33.9		 4yp2B-3ku0A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		6 / 9 PHE A  87
GLY A 111
TYR A 113
ILE A 161
GLU A 166
ARG A 169
 ADE  A 800 (-4.6A)
ADE  A 800 (-4.1A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.21A 5cf9B-3ku0A:
34.1		 5cf9B-3ku0A:
34.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		4 / 7 LEU A  63
ILE A 135
ASP A 141
ASN A  60
 None
 1.06A 5n5dA-3ku0A:
undetectable		 5n5dA-3ku0A:
22.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		5 / 6 VAL A  75
TYR A 113
ILE A 161
GLU A 166
ARG A 169
 ADE  A 800 (-3.9A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.26A 5z3jA-3ku0A:
34.2		 5z3jA-3ku0A:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN
(Suregada
multiflora) 		5 / 12 VAL A  54
LEU A  40
ASP A  69
LEU A 242
ARG A  41
 None
 1.07A 6ew0F-3ku0A:
undetectable		 6ew0F-3ku0A:
16.00