SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kuz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3kuz PLEXIN-C1
(Homo
sapiens) 		5 / 12 ILE A1230
VAL A1302
ILE A1220
VAL A1222
VAL A1224
 None
 0.98A 3iw1A-3kuzA:
undetectable		 3iw1A-3kuzA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3kuz PLEXIN-C1
(Homo
sapiens) 		4 / 6 SER A1221
GLY A1297
ASN A1296
ILE A1300
 None
 1.12A 5j4nA-3kuzA:
undetectable		 5j4nA-3kuzA:
14.32