SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 11 SER A  44
ILE A 243
VAL A 245
ALA A  22
ILE A  24
 GOL  A 284 (-3.2A)
None
None
None
None
 1.17A 1uduA-3kv1A:
undetectable		 1uduA-3kv1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		4 / 4 LEU A  41
SER A  44
TYR A  45
LEU A  23
 GOL  A 284 (-4.3A)
GOL  A 284 (-3.2A)
None
GOL  A 284 ( 4.4A)
 1.26A 1xz1A-3kv1A:
undetectable		 1xz1A-3kv1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		4 / 4 LEU A  41
SER A  44
TYR A  45
LEU A  23
 GOL  A 284 (-4.3A)
GOL  A 284 (-3.2A)
None
GOL  A 284 ( 4.4A)
 1.27A 1xz3A-3kv1A:
undetectable		 1xz3A-3kv1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		6 / 12 GLY A 188
GLY A  61
ASP A 190
ILE A 208
LEU A 140
VAL A  64
 GOL  A 271 (-3.7A)
GOL  A 271 ( 4.5A)
None
None
None
None
 1.32A 2hmyB-3kv1A:
undetectable		 2hmyB-3kv1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 MET A 224
ALA A  22
ALA A  65
ALA A  68
LEU A  46
 None
 1.18A 2x2nB-3kv1A:
undetectable		 2x2nB-3kv1A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 LEU A 246
ALA A 237
VAL A 242
GLY A 187
ILE A 243
 None
None
None
GOL  A 271 ( 4.2A)
None
 1.03A 3d20A-3kv1A:
undetectable		 3d20A-3kv1A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 10 LEU A 246
ALA A 237
VAL A 242
GLY A 187
ILE A 243
 None
None
None
GOL  A 271 ( 4.2A)
None
 1.04A 3oxwB-3kv1A:
undetectable		 3oxwB-3kv1A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 10 LEU A 246
ALA A 237
VAL A 242
GLY A 187
ILE A 243
 None
None
None
GOL  A 271 ( 4.2A)
None
 1.00A 3oxwD-3kv1A:
undetectable		 3oxwD-3kv1A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 GLY A 188
GLY A  59
ILE A 186
VAL A 151
ALA A 119
 GOL  A 271 (-3.7A)
None
None
None
None
 1.14A 4a6dA-3kv1A:
undetectable		 4a6dA-3kv1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 GLY A 188
GLY A  59
ILE A 186
VAL A 151
ALA A 119
 GOL  A 271 (-3.7A)
None
None
None
None
 1.13A 4a6eA-3kv1A:
undetectable		 4a6eA-3kv1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		4 / 7 ASP A 155
GLY A 154
ASP A 157
ASN A 159
 None
GOL  A 271 ( 3.8A)
None
GOL  A 271 (-3.6A)
 1.09A 5no9D-3kv1A:
undetectable		 5no9D-3kv1A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		4 / 4 LEU A 256
LEU A 246
SER A 249
ALA A 247
 None
 1.11A 5uunA-3kv1A:
undetectable		 5uunA-3kv1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 VAL A 221
GLY A 209
ARG A 204
VAL A 207
GLY A 154
 None
None
None
None
GOL  A 271 ( 3.8A)
 1.13A 6brdC-3kv1A:
undetectable		 6brdC-3kv1A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3kv1 TRANSCRIPTIONAL
REPRESSOR
(Aliivibrio
fischeri) 		5 / 12 VAL A 242
VAL A 221
GLY A 209
VAL A 207
GLY A 154
 None
None
None
None
GOL  A 271 ( 3.8A)
 0.99A 6brdC-3kv1A:
undetectable		 6brdC-3kv1A:
14.68