SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 10 PHE D 161
SER D 139
LEU D  81
THR D 130
LEU D 133
 None
 1.37A 1a8uA-3kvdD:
undetectable		 1a8uA-3kvdD:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 ILE D 291
ILE D 235
TYR D 217
ALA D 215
THR D 204
 None
 1.27A 1kijB-3kvdD:
undetectable		 1kijB-3kvdD:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 GLU D 211
GLY D 212
ARG D 214
ALA D 238
ALA D 239
 None
 0.96A 2br4B-3kvdD:
undetectable		 2br4B-3kvdD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 LEU D 111
LEU D 101
GLY D 197
ARG D 145
ALA D 173
 None
 1.17A 2br4D-3kvdD:
undetectable		 2br4D-3kvdD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 SER D 139
GLY D 131
GLY D  80
ALA D  79
LEU D  89
 None
 0.97A 2nyuA-3kvdD:
undetectable		 2nyuA-3kvdD:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 6 ARG D 195
PHE D 194
ILE D 196
PHE D 222
 None
 1.06A 2qeiA-3kvdD:
undetectable		 2qeiA-3kvdD:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 GLY D 229
LEU D 289
VAL D 299
SER D 169
ASP D 136
 None
 1.32A 2vqyA-3kvdD:
undetectable		 2vqyA-3kvdD:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 ALA D  84
PHE D 141
ALA D  79
LEU D 133
 None
 0.88A 4du2A-3kvdD:
undetectable		 4du2A-3kvdD:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 ALA D  84
PHE D 141
ALA D  79
LEU D 133
 None
 0.80A 4du2B-3kvdD:
undetectable		 4du2B-3kvdD:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_ACTA502_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 4 LYS D 319
ARG D 218
GLY D 219
ASP D 136
 None
 1.37A 4ryaA-3kvdD:
0.0		 4ryaA-3kvdD:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 THR D 204
GLY D 290
ALA D 271
ILE D 263
 None
 0.84A 4txnA-3kvdD:
undetectable		 4txnA-3kvdD:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 THR D 204
GLY D 290
ALA D 271
ILE D 263
 None
 0.84A 4txnB-3kvdD:
undetectable		 4txnB-3kvdD:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 THR D 204
GLY D 290
ALA D 271
ILE D 263
 None
 0.85A 4txnC-3kvdD:
undetectable		 4txnC-3kvdD:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		4 / 7 THR D 204
GLY D 290
ALA D 271
ILE D 263
 None
 0.85A 4txnD-3kvdD:
undetectable		 4txnD-3kvdD:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 ALA D 227
GLY D 315
GLY D 219
LEU D 231
ALA D 173
 None
 1.05A 5c0oE-3kvdD:
undetectable		 5c0oE-3kvdD:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3kvd LIPOPROTEIN
(Neisseria
meningitidis) 		5 / 12 GLY D 315
SER D 288
ILE D 246
VAL D 305
VAL D 256
 None
 1.15A 5dpdB-3kvdD:
undetectable		 5dpdB-3kvdD:
18.23