SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kvn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 GLN X 176
TYR X  99
ARG X 166
 None
 0.94A 1gtbA-3kvnX:
undetectable		 1gtbA-3kvnX:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 10 PHE X 197
THR X 193
LEU X 254
LEU X 248
THR X 291
 None
 1.41A 1i18A-3kvnX:
undetectable
1i18B-3kvnX:
undetectable		 1i18A-3kvnX:
12.45
1i18B-3kvnX:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 ALA X 545
VAL X 583
TRP X 603
 None
 0.91A 1micA-3kvnX:
undetectable
1micB-3kvnX:
undetectable		 1micA-3kvnX:
2.39
1micB-3kvnX:
2.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 VAL X 490
ALA X 526
HIS X 546
 None
 0.77A 1q23C-3kvnX:
undetectable		 1q23C-3kvnX:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 VAL X 490
ALA X 526
HIS X 546
 None
 0.74A 1q23H-3kvnX:
undetectable		 1q23H-3kvnX:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 VAL X 490
ALA X 526
HIS X 546
 None
 0.73A 1q23J-3kvnX:
undetectable		 1q23J-3kvnX:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 LEU X 564
LEU X 561
LEU X 512
ALA X 511
LEU X 235
 None
 1.08A 1ya3C-3kvnX:
undetectable		 1ya3C-3kvnX:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 MET X 412
ASN X 413
GLY X 437
HIS X 464
ARG X 496
 None
 1.38A 2cl5B-3kvnX:
undetectable		 2cl5B-3kvnX:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 GLY X 352
THR X 377
GLN X 333
PHE X 541
 None
 1.19A 2qx4A-3kvnX:
2.7
2qx4B-3kvnX:
undetectable		 2qx4A-3kvnX:
16.58
2qx4B-3kvnX:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 MET X 412
ASN X 413
GLY X 437
HIS X 464
ARG X 496
 None
 1.45A 2zvjA-3kvnX:
1.4		 2zvjA-3kvnX:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 6 SER X 584
GLU X 547
SER X 469
ASP X 328
 None
 1.03A 2zvjA-3kvnX:
undetectable		 2zvjA-3kvnX:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 GLY X 144
ASP X 148
GLY X 165
THR X 217
 None
 1.02A 3k4vC-3kvnX:
undetectable		 3k4vC-3kvnX:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 8 ILE X  98
SER X  14
GLY X  12
ASN X 147
 None
C8E  X 623 (-2.9A)
None
C8E  X 623 (-3.1A)
 0.92A 3lslA-3kvnX:
undetectable
3lslD-3kvnX:
undetectable		 3lslA-3kvnX:
16.61
3lslD-3kvnX:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 8 ILE X  98
SER X  16
GLY X  12
ASN X 147
 None
None
None
C8E  X 623 (-3.1A)
 0.86A 3lslA-3kvnX:
undetectable
3lslD-3kvnX:
undetectable		 3lslA-3kvnX:
16.61
3lslD-3kvnX:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 8 ASN X 147
ILE X  98
SER X  14
GLY X  12
 C8E  X 623 (-3.1A)
None
C8E  X 623 (-2.9A)
None
 0.95A 3lslA-3kvnX:
undetectable
3lslD-3kvnX:
undetectable		 3lslA-3kvnX:
16.61
3lslD-3kvnX:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 8 ASN X 147
ILE X  98
SER X  16
GLY X  12
 C8E  X 623 (-3.1A)
None
None
None
 0.88A 3lslA-3kvnX:
undetectable
3lslD-3kvnX:
undetectable		 3lslA-3kvnX:
16.61
3lslD-3kvnX:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 ASP X 300
ARG X 296
ALA X 299
 None
 0.79A 3mbgC-3kvnX:
undetectable		 3mbgC-3kvnX:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 GLY X  92
SER X  14
LEU X 150
HIS X 289
 C8E  X 623 ( 4.4A)
C8E  X 623 (-2.9A)
None
C8E  X 623 (-4.4A)
 0.71A 3o9mA-3kvnX:
undetectable		 3o9mA-3kvnX:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 6 GLY X  92
SER X  14
LEU X 150
HIS X 289
 C8E  X 623 ( 4.4A)
C8E  X 623 (-2.9A)
None
C8E  X 623 (-4.4A)
 0.79A 3o9mB-3kvnX:
undetectable		 3o9mB-3kvnX:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 PHE X 350
ALA X 394
THR X 377
LEU X 330
 None
 1.04A 3t3sC-3kvnX:
undetectable		 3t3sC-3kvnX:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 6 LEU X 312
PRO X 309
GLU X 311
SER X 307
 None
 1.16A 3vlnA-3kvnX:
undetectable		 3vlnA-3kvnX:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 GLN X 539
ASP X 337
GLN X 333
 None
 0.89A 4aztA-3kvnX:
undetectable		 4aztA-3kvnX:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 GLU X 457
PHE X 448
GLY X 506
SER X 508
ASN X 562
 None
 1.41A 4djfA-3kvnX:
undetectable		 4djfA-3kvnX:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 9 ASN X 147
GLY X 145
GLY X 146
GLY X 144
ASP X  13
 C8E  X 623 (-3.1A)
None
C8E  X 623 ( 3.7A)
None
C8E  X 623 ( 4.2A)
 1.29A 4h2fA-3kvnX:
undetectable		 4h2fA-3kvnX:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 LEU X 561
LEU X 186
LEU X 230
ILE X 182
ILE X 142
 None
 1.26A 4j26B-3kvnX:
undetectable		 4j26B-3kvnX:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 LEU X 564
LEU X 561
LEU X 512
ALA X 511
LEU X 235
 None
 0.93A 4ltwA-3kvnX:
undetectable		 4ltwA-3kvnX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 PHE X 448
ALA X 509
SER X 508
ARG X 455
 None
 1.23A 4lv9A-3kvnX:
undetectable
4lv9B-3kvnX:
undetectable		 4lv9A-3kvnX:
21.04
4lv9B-3kvnX:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 VAL X  90
ALA X  89
TYR X  93
PHE X  21
GLY X  19
 None
None
None
C8E  X 624 ( 4.0A)
None
 1.30A 4mm4A-3kvnX:
undetectable		 4mm4A-3kvnX:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 VAL X  90
ALA X  89
TYR X  93
PHE X  21
GLY X  19
 None
None
None
C8E  X 624 ( 4.0A)
None
 1.28A 4mm4B-3kvnX:
undetectable		 4mm4B-3kvnX:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 VAL X  90
ALA X  89
TYR X  93
PHE X  21
GLY X  19
 None
None
None
C8E  X 624 ( 4.0A)
None
 1.29A 4mm6A-3kvnX:
0.0		 4mm6A-3kvnX:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 SER X 615
GLY X 352
ALA X 417
GLY X 395
TYR X 397
 None
 1.30A 4r29A-3kvnX:
undetectable		 4r29A-3kvnX:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 SER X 615
GLY X 352
ALA X 417
GLY X 395
TYR X 397
 None
 1.24A 4r29B-3kvnX:
undetectable		 4r29B-3kvnX:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 SER X 615
GLY X 352
ALA X 417
GLY X 395
TYR X 397
 None
 1.28A 4r29C-3kvnX:
undetectable		 4r29C-3kvnX:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		6 / 12 ALA X 195
LEU X 150
SER X 206
SER X 209
GLY X 146
GLY X  92
 None
None
None
None
C8E  X 623 ( 3.7A)
C8E  X 623 ( 4.4A)
 1.48A 4rzvA-3kvnX:
undetectable		 4rzvA-3kvnX:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 GLN X 529
PRO X 488
ILE X 476
ASP X 475
 None
 1.09A 4w5oA-3kvnX:
2.3		 4w5oA-3kvnX:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 GLN X 529
PRO X 488
ILE X 476
ASP X 475
 None
 1.07A 4z4eA-3kvnX:
2.3		 4z4eA-3kvnX:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 5 GLN X 529
PRO X 488
ILE X 476
ASP X 475
 None
 1.19A 4z4hA-3kvnX:
2.2		 4z4hA-3kvnX:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 ILE X  98
LEU X 167
GLY X 145
GLY X 144
 None
 0.85A 5a06A-3kvnX:
3.2		 5a06A-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 LEU X 616
GLU X 329
GLY X 600
GLY X 599
 None
 0.82A 5a06A-3kvnX:
3.2		 5a06A-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 ILE X  98
LEU X 167
GLY X 145
GLY X 144
 None
 0.85A 5a06B-3kvnX:
3.1		 5a06B-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 LEU X 616
GLU X 329
GLY X 600
GLY X 599
 None
 0.81A 5a06C-3kvnX:
3.3		 5a06C-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 ILE X  98
LEU X 167
GLY X 145
GLY X 144
 None
 0.85A 5a06E-3kvnX:
2.9		 5a06E-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 LEU X 616
GLU X 329
GLY X 600
GLY X 599
 None
 0.82A 5a06E-3kvnX:
2.9		 5a06E-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 LEU X 616
GLU X 329
GLY X 600
GLY X 599
 None
 0.81A 5a06F-3kvnX:
undetectable		 5a06F-3kvnX:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 GLY X 353
LEU X 618
THR X 377
GLY X 395
GLY X 349
 None
 1.06A 5d4uB-3kvnX:
undetectable		 5d4uB-3kvnX:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 GLY X 353
LEU X 618
THR X 377
GLY X 395
GLY X 349
 None
 1.02A 5d4uC-3kvnX:
undetectable		 5d4uC-3kvnX:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 TYR X 141
SER X  16
GLY X 145
VAL X  10
LEU X 167
 None
 1.19A 5g6sB-3kvnX:
3.2
5g6sC-3kvnX:
2.9		 5g6sB-3kvnX:
20.50
5g6sC-3kvnX:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 LEU X  15
GLY X  12
TYR X  93
PHE X 212
LEU X 187
 C8E  X 623 (-4.6A)
None
None
None
None
 1.26A 5kklB-3kvnX:
undetectable		 5kklB-3kvnX:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 MET X 412
ASN X 413
GLY X 437
HIS X 464
ARG X 496
 None
 1.45A 5lsaA-3kvnX:
undetectable		 5lsaA-3kvnX:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 GLY X 256
PHE X 259
HIS X 289
ASN X 285
THR X 291
 None
None
C8E  X 623 (-4.4A)
None
None
 1.38A 5lsuB-3kvnX:
undetectable		 5lsuB-3kvnX:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.38A 5n0rA-3kvnX:
undetectable		 5n0rA-3kvnX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.37A 5n0sA-3kvnX:
undetectable		 5n0sA-3kvnX:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 5 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.42A 5n0tA-3kvnX:
undetectable		 5n0tA-3kvnX:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.36A 5n0wA-3kvnX:
undetectable		 5n0wA-3kvnX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 5 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.36A 5n0wB-3kvnX:
undetectable		 5n0wB-3kvnX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.38A 5n0xA-3kvnX:
undetectable		 5n0xA-3kvnX:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 5 SER X 418
ALA X 393
GLN X 333
THR X 377
 None
 1.37A 5n4iA-3kvnX:
2.7		 5n4iA-3kvnX:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 6 LEU X 378
SER X 619
ARG X 348
GLY X 349
 None
 1.04A 5o4yF-3kvnX:
undetectable		 5o4yF-3kvnX:
2.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 7 GLU X 339
ALA X 430
GLY X 473
TYR X 474
 None
 1.07A 5uxdA-3kvnX:
undetectable		 5uxdA-3kvnX:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 LEU X 216
GLY X 144
ALA X 164
THR X 143
VAL X  10
 None
 1.19A 5x6yA-3kvnX:
undetectable		 5x6yA-3kvnX:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 5 ARG X 496
TYR X 494
GLU X 317
ASP X 608
 None
 1.48A 5yf0A-3kvnX:
0.9		 5yf0A-3kvnX:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_1
(CARNOSINE
N-METHYLTRANSFERASE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		4 / 4 ARG X 496
TYR X 494
GLU X 317
ASP X 608
 None
 1.47A 5yf0B-3kvnX:
0.4		 5yf0B-3kvnX:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		5 / 12 SER X  14
ASN X 213
LEU X 186
ASP X  13
GLY X 145
 C8E  X 623 (-2.9A)
None
None
C8E  X 623 ( 4.2A)
None
 1.36A 6dwnA-3kvnX:
undetectable		 6dwnA-3kvnX:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3kvn ESTERASE ESTA
(Pseudomonas
aeruginosa) 		3 / 3 LEU X  15
ASN X 213
LEU X 167
 C8E  X 623 (-4.6A)
None
None
 0.62A 6exiD-3kvnX:
2.9		 6exiD-3kvnX:
8.55