SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kvs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3kvs C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		5 / 11 ALA B 140
LEU B 105
ASP B 165
GLY B 161
ALA B 168
 None
 1.11A 1b02A-3kvsB:
undetectable		 1b02A-3kvsB:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 LEU A 142
ALA A  40
LEU A  44
ALA A  48
ILE A 154
 None
 0.95A 1fk6A-3kvsA:
undetectable		 1fk6A-3kvsA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK5_A_T44A1008_1
(SERUM ALBUMIN)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		5 / 10 ASP A 155
ALA A 157
LYS A 137
VAL A 136
VAL A  95
 None
 1.48A 1hk5A-3kvsA:
1.8		 1hk5A-3kvsA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kvs C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 ALA B 138
ILE B 139
ILE B  44
VAL B  93
ALA B  96
 None
 1.10A 1uduB-3kvsB:
undetectable		 1uduB-3kvsB:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 ALA A 132
LEU A 161
ILE A 154
SER A 138
LEU A 111
 None
None
None
None
BLA  A 484 ( 4.3A)
 0.94A 1xdkF-3kvsA:
undetectable		 1xdkF-3kvsA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		4 / 8 GLY A  89
ILE A  88
ASN A  53
GLN A  49
 None
 0.77A 2a8tB-3kvsA:
undetectable		 2a8tB-3kvsA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		3 / 3 GLU A   7
ASP A 108
TYR A 156
 None
 0.67A 2yvlB-3kvsA:
undetectable		 2yvlB-3kvsA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		4 / 8 ASN A 151
THR A 152
SER A  37
ARG A  33
 None
None
None
BLA  B 555 (-3.4A)
 1.11A 3kp2A-3kvsA:
undetectable
3kp2B-3kvsA:
1.8		 3kp2A-3kvsA:
21.26
3kp2B-3kvsA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		5 / 9 ASN A 151
THR A 152
ALA A  40
SER A  37
ARG A  33
 None
None
None
None
BLA  B 555 (-3.4A)
 1.49A 3kp6B-3kvsA:
1.6		 3kp6B-3kvsA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 ILE B  98
VAL B  41
SER B  94
TYR B  95
THR A 152
 None
 1.26A 3vrjA-3kvsB:
undetectable
3vrjC-3kvsB:
undetectable		 3vrjA-3kvsB:
22.81
3vrjC-3kvsB:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3kvs C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		3 / 3 LYS B  73
TYR B  74
ARG B  78
 MEN  B  72 (-3.3A)
None
None
 1.35A 4gc9A-3kvsB:
undetectable		 4gc9A-3kvsB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3kvs C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 LEU B 105
ALA B 167
ILE B  97
ALA B  96
ILE B  44
 None
 0.98A 4o2bD-3kvsB:
undetectable		 4o2bD-3kvsB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3kvs C-PHYCOCYANIN BETA
CHAIN
(Galdieria
sulphuraria) 		5 / 12 LEU B 105
ALA B 167
ILE B  97
ALA B  96
ILE B  44
 None
 1.01A 5eypB-3kvsB:
undetectable		 5eypB-3kvsB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3kvs C-PHYCOCYANIN ALPHA
CHAIN
(Galdieria
sulphuraria) 		3 / 3 THR A 152
GLU A  39
ASN A 148
 None
None
BLA  B 555 (-4.2A)
 0.88A 6nj9K-3kvsA:
undetectable		 6nj9K-3kvsA:
18.21