SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 6 ASP A 200
VAL A 166
PHE A 201
PRO A 197
 ADN  A 300 (-3.3A)
ADN  A 300 (-4.1A)
None
ADN  A 300 (-4.9A)
 1.08A 2q6oB-3kw2A:
2.9		 2q6oB-3kw2A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 6 ASP A 200
VAL A 166
PRO A 197
THR A 226
 ADN  A 300 (-3.3A)
ADN  A 300 (-4.1A)
ADN  A 300 (-4.9A)
ADN  A 300 (-4.1A)
 1.41A 2q6oB-3kw2A:
2.9		 2q6oB-3kw2A:
20.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		6 / 9 ALA A 164
VAL A 166
GLY A 196
LEU A 219
LEU A 224
ALA A 229
 ADN  A 300 (-3.5A)
ADN  A 300 (-4.1A)
ADN  A 300 (-3.2A)
ADN  A 300 (-4.1A)
ADN  A 300 (-3.8A)
ADN  A 300 (-3.4A)
 0.84A 2z0yA-3kw2A:
21.9		 2z0yA-3kw2A:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		6 / 9 ALA A 164
VAL A 166
GLY A 196
LEU A 219
LEU A 224
ALA A 229
 ADN  A 300 (-3.5A)
ADN  A 300 (-4.1A)
ADN  A 300 (-3.2A)
ADN  A 300 (-4.1A)
ADN  A 300 (-3.8A)
ADN  A 300 (-3.4A)
 0.97A 2z0yB-3kw2A:
21.9		 2z0yB-3kw2A:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 GLY A 196
LEU A 192
VAL A 151
ILE A 148
LEU A 219
 ADN  A 300 (-3.2A)
None
None
None
ADN  A 300 (-4.1A)
 1.11A 3g9eA-3kw2A:
undetectable		 3g9eA-3kw2A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 102
VAL A 144
ILE A 118
MET A  93
LEU A  97
 None
 1.34A 4a84A-3kw2A:
undetectable		 4a84A-3kw2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 9 VAL A 232
ALA A 164
ARG A 223
ILE A 195
ILE A 193
 None
ADN  A 300 (-3.5A)
None
ADN  A 300 (-4.3A)
None
 1.41A 4oknB-3kw2A:
2.6		 4oknB-3kw2A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 12 VAL A 166
LEU A  97
VAL A 232
GLY A 230
ALA A 229
 ADN  A 300 (-4.1A)
None
None
None
ADN  A 300 (-3.4A)
 1.29A 5iktB-3kw2A:
undetectable		 5iktB-3kw2A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		4 / 6 GLY A 196
PRO A 197
GLU A 205
SER A 202
 ADN  A 300 (-3.2A)
ADN  A 300 (-4.9A)
None
None
 0.97A 5ny7A-3kw2A:
2.0		 5ny7A-3kw2A:
26.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 11 GLU A 198
LEU A 219
ARG A 225
THR A 226
ALA A 229
 None
ADN  A 300 (-4.1A)
None
ADN  A 300 (-4.1A)
ADN  A 300 (-3.4A)
 0.74A 5o96A-3kw2A:
26.2
5o96B-3kw2A:
26.2		 5o96A-3kw2A:
33.46
5o96B-3kw2A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 11 GLU A 198
SER A 218
LEU A 219
ARG A 225
ALA A 229
 None
ADN  A 300 (-3.6A)
ADN  A 300 (-4.1A)
None
ADN  A 300 (-3.4A)
 0.92A 5o96A-3kw2A:
26.2
5o96B-3kw2A:
26.2		 5o96A-3kw2A:
33.46
5o96B-3kw2A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 11 GLY A 199
LEU A 219
ARG A 225
THR A 226
ALA A 229
 None
ADN  A 300 (-4.1A)
None
ADN  A 300 (-4.1A)
ADN  A 300 (-3.4A)
 1.03A 5o96A-3kw2A:
26.2
5o96B-3kw2A:
26.2		 5o96A-3kw2A:
33.46
5o96B-3kw2A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		6 / 11 GLY A 196
SER A 218
ARG A 225
THR A 226
GLU A 227
ALA A 229
 ADN  A 300 (-3.2A)
ADN  A 300 (-3.6A)
None
ADN  A 300 (-4.1A)
None
ADN  A 300 (-3.4A)
 0.50A 5o96G-3kw2A:
26.3		 5o96G-3kw2A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		6 / 11 LEU A 219
SER A 218
ARG A 225
THR A 226
GLU A 227
ALA A 229
 ADN  A 300 (-4.1A)
ADN  A 300 (-3.6A)
None
ADN  A 300 (-4.1A)
None
ADN  A 300 (-3.4A)
 1.48A 5o96G-3kw2A:
26.3		 5o96G-3kw2A:
33.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kw2 PROBABLE R-RNA
METHYLTRANSFERASE
(Porphyromonas
gingivalis) 		5 / 11 SER A 218
LEU A 219
ARG A 225
GLU A 227
ALA A 229
 ADN  A 300 (-3.6A)
ADN  A 300 (-4.1A)
None
None
ADN  A 300 (-3.4A)
 0.78A 5o96G-3kw2A:
26.3		 5o96G-3kw2A:
33.46