SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kw8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.55A 1oe1A-3kw8A:
21.2
1oe1A-3kw8A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.55A 1oe2A-3kw8A:
12.7
1oe2A-3kw8A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.58A 1oe3A-3kw8A:
21.3
1oe3A-3kw8A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 SER A 120
ARG A 128
HIS A 104
HIS A 156
None
0.91A 1s19A-3kw8A:
undetectable
1s19A-3kw8A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.49A 2fqdA-3kw8A:
17.8
2fqdA-3kw8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.44A 2fqeA-3kw8A:
17.8
2fqeA-3kw8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.46A 2fqfA-3kw8A:
17.8
2fqfA-3kw8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.48A 2fqgA-3kw8A:
undetectable
2fqgA-3kw8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
5 / 12 ILE A 193
ALA A 213
VAL A 304
PHE A 233
HIS A 234
None
None
None
None
CU  A 404 (-3.1A)
1.06A 2qo4A-3kw8A:
undetectable
2qo4A-3kw8A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
5 / 12 ILE A 193
ALA A 213
VAL A 304
PHE A 233
HIS A 234
None
None
None
None
CU  A 404 (-3.1A)
1.03A 2qo6A-3kw8A:
undetectable
2qo6A-3kw8A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 TRP A 240
GLN A 272
TRP A 284
None
1.02A 2vqyA-3kw8A:
undetectable
2vqyA-3kw8A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.54A 2xxgA-3kw8A:
8.2
2xxgA-3kw8A:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.56A 2xxgC-3kw8A:
11.1
2xxgC-3kw8A:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 156
HIS A 104
HIS A 154
None
0.71A 3ag4A-3kw8A:
undetectable
3ag4A-3kw8A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 156
HIS A 104
HIS A 154
None
0.75A 3ag4N-3kw8A:
undetectable
3ag4N-3kw8A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 ILE A 193
PHE A 233
ILE A 221
THR A 225
None
1.02A 3ia4A-3kw8A:
undetectable
3ia4A-3kw8A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 287
HIS A 234
HIS A 236
CU  A 403 (-3.5A)
CU  A 404 (-3.1A)
CU  A 403 ( 3.2A)
0.80A 3mihA-3kw8A:
undetectable
3mihA-3kw8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 287
HIS A 236
MET A 285
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
CU  A 403 ( 4.6A)
0.60A 3mihA-3kw8A:
undetectable
3mihA-3kw8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 4 HIS A 231
CYH A 288
HIS A 293
MET A 298
CU  A 401 (-3.0A)
CU  A 401 (-2.1A)
CU  A 401 (-3.0A)
CU  A 401 (-3.4A)
0.48A 4ef3A-3kw8A:
17.7
4ef3A-3kw8A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
5 / 12 MET A  53
LEU A  51
VAL A 103
LEU A 101
LEU A  87
None
1.23A 4m11A-3kw8A:
undetectable
4m11A-3kw8A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 GLY A  66
ALA A  72
GLY A  76
PRO A  77
None
0.93A 4u9uA-3kw8A:
undetectable
4u9uA-3kw8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 GLY A  66
ALA A  72
GLY A  76
PRO A  77
None
0.94A 4u9uB-3kw8A:
undetectable
4u9uB-3kw8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 ASP A  85
VAL A 179
LEU A 106
None
0.65A 5e5jB-3kw8A:
undetectable
5e5jB-3kw8A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 ILE A  89
LEU A  78
HIS A 154
VAL A 103
None
PGE  A 612 (-4.8A)
None
None
1.16A 5jmnB-3kw8A:
undetectable
5jmnB-3kw8A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mhwA-3kw8A:
11.6
5mhwA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.89A 5mhxA-3kw8A:
18.9
5mhxA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mhyA-3kw8A:
18.9
5mhyA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mhzA-3kw8A:
11.6
5mhzA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mi1A-3kw8A:
11.6
5mi1A-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mi2A-3kw8A:
11.6
5mi2A-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5miaA-3kw8A:
11.6
5miaA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mibA-3kw8A:
11.6
5mibA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5micA-3kw8A:
11.6
5micA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5midA-3kw8A:
18.9
5midA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.90A 5mieA-3kw8A:
11.7
5mieA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 5 HIS A 289
HIS A 234
HIS A 287
HIS A 236
CU  A 402 (-3.2A)
CU  A 404 (-3.1A)
CU  A 403 (-3.5A)
CU  A 403 ( 3.2A)
0.89A 5migA-3kw8A:
11.6
5migA-3kw8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 156
HIS A 158
HIS A 164
None
0.91A 5oexA-3kw8A:
undetectable
5oexA-3kw8A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 6 GLN A 272
VAL A 219
ALA A 213
THR A 214
None
0.90A 6cduB-3kw8A:
undetectable
6cduC-3kw8A:
undetectable
6cduB-3kw8A:
21.05
6cduC-3kw8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 7 GLN A 272
VAL A 219
ALA A 213
THR A 214
None
0.93A 6cduC-3kw8A:
undetectable
6cduD-3kw8A:
undetectable
6cduC-3kw8A:
21.05
6cduD-3kw8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
4 / 7 ALA A 213
THR A 214
GLN A 272
VAL A 219
None
0.93A 6cduF-3kw8A:
undetectable
6cduJ-3kw8A:
undetectable
6cduF-3kw8A:
21.05
6cduJ-3kw8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kw8 PUTATIVE COPPER
OXIDASE

(Streptomyces
coelicolor)
3 / 3 HIS A 156
HIS A 104
HIS A 154
None
0.74A 6giqa-3kw8A:
undetectable
6giqa-3kw8A:
19.77