SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kwk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SA1_D_PODD701_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3kwk	PUTATIVE NADH DEHYDROGENASE/NAD(P) H NITROREDUCTASE (Bacteroides thetaiotaomicron)	5 / 12	VAL A 81 ALA A 105 LEU A 102 VAL A 144 ALA A 143	None	1.17A	1sa1C-3kwkA: undetectable 1sa1D-3kwkA: undetectable	1sa1C-3kwkA: 18.36 1sa1D-3kwkA: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARU_A_PNXA608_1 (CHITINASE A)	3kwk	PUTATIVE NADH DEHYDROGENASE/NAD(P) H NITROREDUCTASE (Bacteroides thetaiotaomicron)	4 / 6	TRP A 121 SER A 126 ALA A 127 ASP A 124	None	1.30A	3aruA-3kwkA: undetectable	3aruA-3kwkA: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_0 (METHYLTRANSFERASE)	3kwk	PUTATIVE NADH DEHYDROGENASE/NAD(P) H NITROREDUCTASE (Bacteroides thetaiotaomicron)	5 / 12	LEU A 164 VAL A 157 TYR A 161 ILE A 174 ALA A 129	None	1.12A	5n5dB-3kwkA: undetectable	5n5dB-3kwkA: 20.42