SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		4 / 7 GLU C  64
LEU C  62
VAL C 147
LEU C 129
 None
 1.03A 1hk3A-3kwvC:
undetectable		 1hk3A-3kwvC:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 ILE C  83
ILE C 225
ILE C 151
LEU C 129
VAL C  70
 None
 1.19A 2qo5A-3kwvC:
undetectable		 2qo5A-3kwvC:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		5 / 9 PHE C 247
ILE C 225
VAL C  66
GLY C 152
VAL C  70
 None
 1.01A 4r20B-3kwvC:
undetectable		 4r20B-3kwvC:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU C 188
PRO C 238
ALA C 237
GLU C 249
PHE C 247
 None
 1.34A 5x6yA-3kwvC:
undetectable		 5x6yA-3kwvC:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		5 / 12 LEU C 188
PRO C 238
ALA C 237
GLU C 249
PHE C 247
 None
 1.34A 5x6yC-3kwvC:
undetectable		 5x6yC-3kwvC:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		3 / 3 ARG C 230
LYS C  65
TYR C 148
 None
 1.31A 6gnaA-3kwvC:
undetectable		 6gnaA-3kwvC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3kwv LETHAL FACTOR
(Bacillus
anthracis) 		3 / 3 ARG C 230
LYS C  65
TYR C 148
 None
 1.31A 6gnbA-3kwvC:
undetectable		 6gnbA-3kwvC:
20.54