SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 TRP X   7
ALA X  13
VAL X  11
 None
 0.84A 2izqA-3kx0X:
undetectable
2izqB-3kx0X:
undetectable		 2izqA-3kx0X:
13.58
2izqB-3kx0X:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 ALA X  13
VAL X  11
TRP X   7
 None
 0.82A 3l8lA-3kx0X:
undetectable
3l8lB-3kx0X:
undetectable		 3l8lA-3kx0X:
13.58
3l8lB-3kx0X:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 7 LEU X  31
VAL X  78
TYR X  72
LEU X 125
 None
 1.04A 4b3qA-3kx0X:
undetectable		 4b3qA-3kx0X:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL X  62
TYR X  63
VAL X  29
HIS X  36
 None
 0.90A 5eckA-3kx0X:
undetectable		 5eckA-3kx0X:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL X  62
TYR X  63
VAL X  29
HIS X  36
 None
 0.94A 5eckD-3kx0X:
undetectable		 5eckD-3kx0X:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL X  62
TYR X  63
VAL X  29
HIS X  36
 None
 0.90A 5eclA-3kx0X:
undetectable		 5eclA-3kx0X:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3kx0 UNCHARACTERIZED
PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 7 ALA X  59
VAL X  62
TYR X  63
VAL X  29
HIS X  36
 None
 1.16A 5ecoD-3kx0X:
undetectable		 5ecoD-3kx0X:
16.28