SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kxe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3kxe TOXIN PROTEIN PARE-1
(Caulobacter
vibrioides) 		3 / 4 VAL A  27
TRP A  25
TRP A  18
 None
 1.36A 1gmkA-3kxeA:
undetectable
1gmkB-3kxeA:
undetectable		 1gmkA-3kxeA:
6.93
1gmkB-3kxeA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3kxe TOXIN PROTEIN PARE-1
(Caulobacter
vibrioides) 		3 / 4 VAL A  27
TRP A  25
TRP A  18
 None
 1.44A 1gmkC-3kxeA:
undetectable
1gmkD-3kxeA:
undetectable		 1gmkC-3kxeA:
6.93
1gmkD-3kxeA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3kxe ANTITOXIN PROTEIN
PARD-1
TOXIN PROTEIN PARE-1
(Caulobacter
vibrioides) 		4 / 7 VAL A  75
ILE A  82
GLY C  58
ARG A   8
 None
 0.79A 3bjwF-3kxeA:
undetectable		 3bjwF-3kxeA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3kxe ANTITOXIN PROTEIN
PARD-1
TOXIN PROTEIN PARE-1
(Caulobacter
vibrioides) 		4 / 8 PHE C  72
PHE C  69
PHE C  67
ALA A  10
 None
 0.84A 3t3sD-3kxeC:
undetectable		 3t3sD-3kxeC:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kxe TOXIN PROTEIN PARE-1
(Caulobacter
vibrioides) 		4 / 4 TYR A  73
THR A  40
VAL A  70
ILE A  81
 None
 1.49A 4jx1F-3kxeA:
undetectable		 4jx1F-3kxeA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3kxe TOXIN PROTEIN PARE-1
ANTITOXIN PROTEIN
PARD-1
(Caulobacter
vibrioides;
Caulobacter
vibrioides) 		4 / 5 GLU C  59
SER A   7
ARG A  58
SER C  61
 None
 1.05A 4k17B-3kxeC:
undetectable		 4k17B-3kxeC:
9.47