SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3kxf SB27 T CELL RECEPTOR
ALPHA CHAIN
(Homo
sapiens) 		4 / 7 ASP D  17
THR D  77
ILE D  59
ASN D  57
 None
 1.15A 2jc9A-3kxfD:
undetectable		 2jc9A-3kxfD:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kxf SB27 T CELL RECEPTOR
ALPHA CHAIN
(Homo
sapiens) 		4 / 8 ASN D  57
GLU D  58
GLU D  55
TYR D  32
 None
 1.01A 4mj8A-3kxfD:
undetectable
4mj8C-3kxfD:
undetectable		 4mj8A-3kxfD:
17.56
4mj8C-3kxfD:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3kxf SB27 T CELL RECEPTOR
ALPHA CHAIN
(Homo
sapiens) 		3 / 3 ASP D 153
ASN D 192
SER D 183
 None
 0.77A 4obwA-3kxfD:
undetectable		 4obwA-3kxfD:
20.38