SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 5 LEU A  87
LEU A  51
LEU A  25
GLY A  66
 None
 0.85A 1a4lC-3kxqA:
6.5		 1a4lC-3kxqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		5 / 11 ILE A  97
SER A 154
LEU A 155
PRO A 156
ILE A 166
 None
 1.20A 1dg5A-3kxqA:
undetectable		 1dg5A-3kxqA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		5 / 12 GLN A  68
ILE A  63
GLY A  11
SER A 238
LYS A 240
 None
None
None
None
EDO  A 302 (-3.1A)
 1.04A 3sueA-3kxqA:
undetectable		 3sueA-3kxqA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 ASP A 249
GLY A  31
THR A 246
PHE A  40
 None
 1.16A 3vnsA-3kxqA:
2.4		 3vnsA-3kxqA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 8 ASP A  81
ILE A  82
GLN A  68
GLY A  67
 None
 0.81A 4acaC-3kxqA:
3.4		 4acaC-3kxqA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 6 ILE A  96
GLY A  67
ILE A  63
LEU A 233
 None
None
None
NO3  A 310 (-3.9A)
 0.73A 4o8fB-3kxqA:
undetectable		 4o8fB-3kxqA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 LYS A  88
LEU A  87
GLY A  66
GLY A  67
 None
 0.63A 5a06A-3kxqA:
undetectable		 5a06A-3kxqA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 LYS A  88
LEU A  87
GLY A  66
GLY A  67
 None
 0.64A 5a06B-3kxqA:
2.5		 5a06B-3kxqA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 LYS A  88
LEU A  87
GLY A  66
GLY A  67
 None
 0.66A 5a06C-3kxqA:
2.7		 5a06C-3kxqA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 LYS A  88
LEU A  87
GLY A  66
GLY A  67
 None
 0.64A 5a06E-3kxqA:
2.4		 5a06E-3kxqA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		4 / 7 LYS A  88
LEU A  87
GLY A  66
GLY A  67
 None
 0.64A 5a06F-3kxqA:
2.5		 5a06F-3kxqA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3kxq TRIOSEPHOSPHATE
ISOMERASE
(Bartonella
henselae) 		5 / 9 ALA A  84
SER A  83
ALA A  92
ALA A  48
GLY A  67
 None
 1.12A 6bklE-3kxqA:
undetectable
6bklF-3kxqA:
undetectable
6bklG-3kxqA:
undetectable
6bklH-3kxqA:
undetectable		 6bklE-3kxqA:
6.91
6bklF-3kxqA:
6.91
6bklG-3kxqA:
6.91
6bklH-3kxqA:
6.91