SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kxr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3kxr MAGNESIUM
TRANSPORTER,
PUTATIVE
(Shewanella
oneidensis) 		4 / 8 LEU A  47
ALA A 131
ILE A  56
GLY A 161
 None
 0.65A 1sv9A-3kxrA:
undetectable		 1sv9A-3kxrA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VFT_A_SORA1419_0
(XYLITOL OXIDASE)		 3kxr MAGNESIUM
TRANSPORTER,
PUTATIVE
(Shewanella
oneidensis) 		5 / 12 VAL A 104
PHE A  80
THR A 103
GLU A 149
ARG A 162
 None
 1.43A 2vftA-3kxrA:
0.0		 2vftA-3kxrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3kxr MAGNESIUM
TRANSPORTER,
PUTATIVE
(Shewanella
oneidensis) 		4 / 6 ASP A  89
LEU A  91
ASP A 108
HIS A 112
 None
 1.05A 3bj8C-3kxrA:
undetectable
3bj8D-3kxrA:
undetectable		 3bj8C-3kxrA:
21.80
3bj8D-3kxrA:
21.80