SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kxy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
EXSE
(Pseudomonas
aeruginosa) 		4 / 4 HIS T  22
LEU A 119
LEU A 115
LEU A  23
 None
 1.14A 1a4lD-3kxyT:
undetectable		 1a4lD-3kxyT:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
EXSE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  76
GLY A  87
VAL A  95
ARG T  38
LEU A 118
 None
 1.17A 1nhzA-3kxyA:
undetectable		 1nhzA-3kxyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  25
LEU A  46
LEU A  52
LEU A   3
 None
 0.95A 2ab2A-3kxyA:
undetectable		 2ab2A-3kxyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
EXSE
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		3 / 3 PHE A  14
PHE T  23
PHE A  35
 None
 0.82A 2od9A-3kxyA:
undetectable		 2od9A-3kxyA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  52
LEU A  44
VAL A  41
LEU A 115
THR A 114
 None
 1.37A 2q7kA-3kxyA:
undetectable		 2q7kA-3kxyA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
EXSE
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		3 / 3 PHE A  14
PHE T  23
PHE A  35
 None
 0.82A 2qqgA-3kxyA:
undetectable		 2qqgA-3kxyA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  87
LEU A  53
LEU A  54
GLU A  55
 None
 0.85A 4mwzB-3kxyA:
undetectable		 4mwzB-3kxyA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  18
LEU A  33
GLU A  13
PHE A  14
GLY A  16
 None
 1.27A 5il1A-3kxyA:
undetectable		 5il1A-3kxyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3kxy EXOENZYME S
SYNTHESIS PROTEIN C
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  18
LEU A  33
GLU A  13
PHE A  14
GLY A  16
 None
 1.22A 5k7uA-3kxyA:
undetectable		 5k7uA-3kxyA:
21.65