SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ky7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 TYR A   5
LEU A  17
VAL A 151
ILE A 150
PHE A 108
 None
 1.40A 1q6iB-3ky7A:
undetectable		 1q6iB-3ky7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ILE A  33
THR A 147
ASP A 148
ALA A 149
SER A  20
 None
 1.11A 1rjdA-3ky7A:
undetectable		 1rjdA-3ky7A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ILE A  33
THR A 147
ASP A 148
ALA A 149
SER A  20
 None
 1.11A 1rjdB-3ky7A:
undetectable		 1rjdB-3ky7A:
22.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		7 / 12 PRO A  87
GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
None
OCS  A  86 ( 3.8A)
None
None
None
None
 0.66A 1uakA-3ky7A:
19.8		 1uakA-3ky7A:
43.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		7 / 12 PRO A  87
SER A 130
VAL A 135
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
OCS  A  86 ( 3.8A)
None
None
None
None
None
 0.70A 1uakA-3ky7A:
19.8		 1uakA-3ky7A:
43.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 None
OCS  A  86 ( 3.8A)
None
None
None
None
 0.63A 3axzA-3ky7A:
20.6		 3axzA-3ky7A:
44.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 PRO A  87
GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
 OCS  A  86 ( 2.5A)
None
OCS  A  86 ( 3.8A)
None
None
None
 0.64A 3axzA-3ky7A:
20.6		 3axzA-3ky7A:
44.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 GLY A 139
ALA A 143
THR A 147
ILE A 106
 None
 0.80A 3jusA-3ky7A:
undetectable		 3jusA-3ky7A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 GLY A 139
ALA A 143
THR A 147
ILE A 106
 None
 0.80A 3jusA-3ky7A:
undetectable		 3jusA-3ky7A:
20.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 None
OCS  A  86 ( 3.8A)
None
None
None
None
 0.67A 4yvgA-3ky7A:
19.7		 4yvgA-3ky7A:
44.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 PRO A  87
GLY A 111
GLU A 114
GLY A 138
GLY A 139
 OCS  A  86 ( 2.5A)
None
None
None
None
 1.06A 4yvgA-3ky7A:
19.7		 4yvgA-3ky7A:
44.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 PRO A  87
GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
 OCS  A  86 ( 2.5A)
None
OCS  A  86 ( 3.8A)
None
None
None
 0.63A 4yvgA-3ky7A:
19.7		 4yvgA-3ky7A:
44.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 LEU A 211
THR A 214
ASP A 231
THR A 228
GLY A 172
 None
 1.43A 5m5kB-3ky7A:
undetectable		 5m5kB-3ky7A:
20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 PRO A  87
GLY A 111
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
None
None
None
None
None
 0.66A 5wyqA-3ky7A:
20.2		 5wyqA-3ky7A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		7 / 12 PRO A  87
SER A 130
VAL A 135
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
OCS  A  86 ( 3.8A)
None
None
None
None
None
 0.72A 5wyqA-3ky7A:
20.2		 5wyqA-3ky7A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		8 / 12 PRO A  87
GLY A 111
SER A 130
TYR A 134
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
None
OCS  A  86 ( 3.8A)
None
None
None
None
None
 0.73A 5wyqB-3ky7A:
20.8		 5wyqB-3ky7A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 PRO A  87
SER A 130
TYR A 134
LEU A 136
GLY A 138
PRO A 142
 OCS  A  86 ( 2.5A)
OCS  A  86 ( 3.8A)
None
None
None
None
 1.22A 5wyqB-3ky7A:
20.8		 5wyqB-3ky7A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 TYR A 116
PRO A  87
GLY A 111
ILE A 129
GLY A 139
 OCS  A  86 ( 4.6A)
OCS  A  86 ( 2.5A)
None
None
None
 0.98A 5wyqB-3ky7A:
20.8		 5wyqB-3ky7A:
39.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		7 / 12 PRO A  87
GLY A 111
SER A 130
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
None
OCS  A  86 ( 3.8A)
None
None
None
None
 0.74A 5zhmB-3ky7A:
10.9		 5zhmB-3ky7A:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		7 / 12 PRO A  87
SER A 130
VAL A 135
LEU A 136
GLY A 138
GLY A 139
PRO A 142
 OCS  A  86 ( 2.5A)
OCS  A  86 ( 3.8A)
None
None
None
None
None
 0.67A 5zhmB-3ky7A:
10.9		 5zhmB-3ky7A:
45.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3ky7 TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 HIS A  19
ASN A  18
LEU A  17
 None
 0.87A 6f7lB-3ky7A:
undetectable		 6f7lB-3ky7A:
20.50