SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ky8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DHF_A_FOLA187_0 (DIHYDROFOLATE REDUCTASE)	3ky8	PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN (Shewanella loihica)	5 / 12	ALA A 8 THR A 54 PRO A 66 LEU A 48 THR A 134	UNL A 179 ( 3.9A) SO4 A 181 (-3.6A) None None UNL A 179 ( 4.1A)	1.11A	1dhfA-3ky8A: 13.9	1dhfA-3ky8A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YQZ_A_SAMA301_0 (HYPOTHETICAL PROTEIN TTHA0223)	3ky8	PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN (Shewanella loihica)	5 / 12	ILE A 4 LEU A -4 ALA A 101 LEU A 127 LEU A 96	None	0.99A	2yqzA-3ky8A: undetectable	2yqzA-3ky8A: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB151_0 (ILEAL BILE ACID-BINDING PROTEIN)	3ky8	PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN (Shewanella loihica)	5 / 10	ILE A 15 ILE A 7 PHE A 38 TYR A 67 LEU A 25	UNL A 180 ( 4.3A) None UNL A 179 ( 3.8A) None None	1.35A	3elzB-3ky8A: undetectable	3elzB-3ky8A: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_1 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	3ky8	PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN (Shewanella loihica)	5 / 12	LEU A 41 ASN A 104 ASN A 3 LEU A 123 ILE A 128	None	1.40A	5dv4A-3ky8A: undetectable	5dv4A-3ky8A: 19.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DHF_A_FOLA187_0","DIHYDROFOLATE REDUCTASE","3ky8","PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN","Shewanella loihica",5,"ALA A   8;THR A  54;PRO A  66;LEU A  48;THR A 134","UNL A 179 ( 3.9A);SO4 A 181 (-3.6A);None;None;UNL A 179 ( 4.1A)","1.11A","1dhfA-3ky8A:13.9","1dhfA-3ky8A:25.00"],["2YQZ_A_SAMA301_0","HYPOTHETICAL PROTEIN TTHA0223","3ky8","PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN","Shewanella loihica",5,"ILE A   4;LEU A  -4;ALA A 101;LEU A 127;LEU A  96","None","0.99A","2yqzA-3ky8A:undetectable","2yqzA-3ky8A:19.62"],["3ELZ_B_CHDB151_0","ILEAL BILE ACID-BINDING PROTEIN","3ky8","PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN","Shewanella loihica",5,"ILE A  15;ILE A   7;PHE A  38;TYR A  67;LEU A  25","UNL A 180 ( 4.3A);None;UNL A 179 ( 3.8A);None;None","1.35A","3elzB-3ky8A:undetectable","3elzB-3ky8A:21.50"],["5DV4_A_NMYA601_1","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","3ky8","PUTATIVE RIBOFLAVIN BIOSYNTHESIS PROTEIN","Shewanella loihica",5,"LEU A  41;ASN A 104;ASN A   3;LEU A 123;ILE A 128","None","1.40A","5dv4A-3ky8A:undetectable","5dv4A-3ky8A:19.95"]]