SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 LEU A 220
LEU A 192
PHE A 184
ILE A 158
LEU A 155
 None
 1.10A 2oipD-3kyfA:
undetectable		 2oipD-3kyfA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 LEU A 220
LEU A 192
PHE A 184
ILE A 158
LEU A 155
 None
 1.12A 2oipE-3kyfA:
undetectable		 2oipE-3kyfA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 4 GLU A 172
GLY A 169
THR A 210
GLU A 168
 None
 1.23A 3e9xA-3kyfA:
undetectable		 3e9xA-3kyfA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 10 ALA A 224
GLN A 225
PHE A 217
VAL A 136
ILE A 138
 None
 1.00A 3falA-3kyfA:
undetectable		 3falA-3kyfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 LEU A 220
LEU A 192
PHE A 184
ILE A 158
LEU A 155
 None
 1.03A 3hj3D-3kyfA:
undetectable		 3hj3D-3kyfA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 9 PHE A 217
VAL A 215
LEU A 190
ILE A 158
ALA A 186
 None
 0.90A 3mdvA-3kyfA:
undetectable		 3mdvA-3kyfA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 PHE A 217
VAL A 215
LEU A 190
ILE A 158
ALA A 186
 None
 0.90A 3mdvB-3kyfA:
undetectable		 3mdvB-3kyfA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 ALA A 224
GLN A 225
PHE A 217
VAL A 136
ILE A 138
 None
 0.89A 3oapA-3kyfA:
undetectable		 3oapA-3kyfA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 12 ALA A 224
GLN A 225
PHE A 217
VAL A 136
ILE A 138
 None
 0.87A 3uvvB-3kyfA:
undetectable		 3uvvB-3kyfA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 6 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.23A 4mi4A-3kyfA:
undetectable		 4mi4A-3kyfA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 7 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.23A 4mi4A-3kyfA:
undetectable
4mi4C-3kyfA:
undetectable		 4mi4A-3kyfA:
25.40
4mi4C-3kyfA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 8 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.22A 4mj8A-3kyfA:
undetectable
4mj8C-3kyfA:
undetectable		 4mj8A-3kyfA:
24.79
4mj8C-3kyfA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 7 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.25A 4mj8C-3kyfA:
undetectable		 4mj8C-3kyfA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 7 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.26A 4r87I-3kyfA:
undetectable		 4r87I-3kyfA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		5 / 11 ASP A  62
HIS A  51
VAL A  50
LEU A  59
THR A  58
 None
 1.18A 4yhaC-3kyfA:
undetectable		 4yhaC-3kyfA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 6 ARG A 174
LYS A 146
LEU A 145
PHE A 167
 None
 1.10A 5w97C-3kyfA:
undetectable
5w97J-3kyfA:
undetectable		 5w97C-3kyfA:
23.31
5w97J-3kyfA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
putida) 		4 / 6 PRO A  33
ILE A  35
GLY A  83
GLU A  82
 None
 1.05A 6gqiA-3kyfA:
undetectable		 6gqiA-3kyfA:
18.08