SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 LEU B  68
GLU B  98
ALA B 101
VAL B 104
 None
 1.02A 1sn5A-3kyjB:
undetectable		 1sn5A-3kyjB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.88A 1v55A-3kyjB:
undetectable
1v55J-3kyjB:
undetectable		 1v55A-3kyjB:
15.09
1v55J-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.87A 2dyrN-3kyjB:
undetectable
2dyrW-3kyjB:
undetectable		 2dyrN-3kyjB:
15.09
2dyrW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 2einN-3kyjB:
undetectable
2einW-3kyjB:
undetectable		 2einN-3kyjB:
15.09
2einW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3kyj PUTATIVE HISTIDINE
PROTEIN KINASE
CHEY6 PROTEIN
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 12 ARG B  15
VAL A  59
LEU A  14
ILE A  11
SER B  20
 None
 1.09A 2fj1A-3kyjB:
undetectable		 2fj1A-3kyjB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3kyj CHEY6 PROTEIN
PUTATIVE HISTIDINE
PROTEIN KINASE
(Rhodobacter
sphaeroides) 		4 / 4 ARG A  58
GLY A  61
GLU A  66
SER B  20
 None
 1.37A 2xctS-3kyjA:
undetectable
2xctU-3kyjA:
undetectable		 2xctS-3kyjA:
11.85
2xctU-3kyjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 3ablA-3kyjB:
undetectable
3ablJ-3kyjB:
undetectable		 3ablA-3kyjB:
15.09
3ablJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 8 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.84A 3abmN-3kyjB:
undetectable
3abmW-3kyjB:
undetectable		 3abmN-3kyjB:
15.09
3abmW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.96A 3ag1N-3kyjB:
undetectable
3ag1W-3kyjB:
undetectable		 3ag1N-3kyjB:
15.09
3ag1W-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.91A 3ag3A-3kyjB:
undetectable
3ag3J-3kyjB:
undetectable		 3ag3A-3kyjB:
15.09
3ag3J-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 8 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.87A 3ag3N-3kyjB:
undetectable
3ag3W-3kyjB:
undetectable		 3ag3N-3kyjB:
15.09
3ag3W-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 8 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.89A 3asoN-3kyjB:
undetectable
3asoW-3kyjB:
undetectable		 3asoN-3kyjB:
15.09
3asoW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3kyj PUTATIVE HISTIDINE
PROTEIN KINASE
(Rhodobacter
sphaeroides) 		4 / 6 VAL A  84
LEU A  75
CYH A 134
SER A 135
 None
 1.16A 3b6rB-3kyjA:
undetectable		 3b6rB-3kyjA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		6 / 11 GLY B 100
ALA B 101
ASP B 102
ILE B  53
LEU B  73
VAL B  61
 None
 1.19A 3em4A-3kyjB:
undetectable		 3em4A-3kyjB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		3 / 3 LEU B  52
MET B   6
ASP B   9
 None
 0.85A 3v5wA-3kyjB:
undetectable		 3v5wA-3kyjB:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.90A 3wg7N-3kyjB:
undetectable
3wg7W-3kyjB:
undetectable		 3wg7N-3kyjB:
15.09
3wg7W-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3kyj PUTATIVE HISTIDINE
PROTEIN KINASE
(Rhodobacter
sphaeroides) 		4 / 6 LEU A 127
MET A  26
LEU A 101
VAL A 115
 None
 1.12A 4okbA-3kyjA:
undetectable		 4okbA-3kyjA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 5b1aA-3kyjB:
undetectable
5b1aJ-3kyjB:
undetectable		 5b1aA-3kyjB:
15.09
5b1aJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.91A 5b1bN-3kyjB:
undetectable
5b1bW-3kyjB:
undetectable		 5b1bN-3kyjB:
15.09
5b1bW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.94A 5b3sA-3kyjB:
undetectable
5b3sJ-3kyjB:
undetectable		 5b3sA-3kyjB:
15.09
5b3sJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 5b3sN-3kyjB:
undetectable
5b3sW-3kyjB:
undetectable		 5b3sN-3kyjB:
15.09
5b3sW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.93A 5iy5N-3kyjB:
undetectable
5iy5W-3kyjB:
undetectable		 5iy5N-3kyjB:
15.09
5iy5W-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		5 / 10 LEU B  55
ALA B  77
ASP B  51
VAL B   8
ILE B  53
 None
 0.99A 5kr1A-3kyjB:
undetectable		 5kr1A-3kyjB:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.94A 5xdxA-3kyjB:
undetectable
5xdxJ-3kyjB:
undetectable		 5xdxA-3kyjB:
15.09
5xdxJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 5z86N-3kyjB:
undetectable
5z86W-3kyjB:
undetectable		 5z86N-3kyjB:
15.09
5z86W-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 6 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.94A 5zcoN-3kyjB:
undetectable
5zcoW-3kyjB:
undetectable		 5zcoN-3kyjB:
15.09
5zcoW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.94A 5zcpA-3kyjB:
undetectable
5zcpJ-3kyjB:
undetectable		 5zcpA-3kyjB:
15.09
5zcpJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 8 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.92A 5zcpN-3kyjB:
undetectable
5zcpW-3kyjB:
undetectable		 5zcpN-3kyjB:
15.09
5zcpW-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kyj CHEY6 PROTEIN
(Rhodobacter
sphaeroides) 		4 / 7 ILE B   7
MET B 128
THR B 127
LEU B 124
 None
 0.93A 5zcqA-3kyjB:
undetectable
5zcqJ-3kyjB:
undetectable		 5zcqA-3kyjB:
15.09
5zcqJ-3kyjB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3kyj PUTATIVE HISTIDINE
PROTEIN KINASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  90
GLY A  83
ALA A  82
ASP A  81
ILE A 131
 None
 1.04A 6dwnD-3kyjA:
undetectable		 6dwnD-3kyjA:
18.52