SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kyq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		5 / 12 ARG A 129
LEU A  93
LEU A  94
LEU A 123
ALA A  22
 None
 1.06A 1gseB-3kyqA:
undetectable		 1gseB-3kyqA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		5 / 12 LEU A 153
GLU A  61
LEU A 160
ILE A  47
SER A  51
 None
 1.18A 2ydoA-3kyqA:
undetectable		 2ydoA-3kyqA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		4 / 7 GLU A  95
GLU A 145
TYR A  69
ARG A  56
 None
 1.04A 2zt7A-3kyqA:
undetectable		 2zt7A-3kyqA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		4 / 6 ILE A 152
LEU A  94
PHE A  91
HIS A  67
 None
 0.99A 5vkqA-3kyqA:
undetectable
5vkqB-3kyqA:
undetectable		 5vkqA-3kyqA:
7.64
5vkqB-3kyqA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		4 / 6 ILE A 152
LEU A  94
PHE A  91
HIS A  67
 None
 0.99A 5vkqB-3kyqA:
undetectable
5vkqC-3kyqA:
undetectable		 5vkqB-3kyqA:
7.64
5vkqC-3kyqA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		4 / 6 ILE A 152
LEU A  94
PHE A  91
HIS A  67
 None
 0.98A 5vkqC-3kyqA:
undetectable
5vkqD-3kyqA:
undetectable		 5vkqC-3kyqA:
7.64
5vkqD-3kyqA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kyq SYNAPTOBREVIN
HOMOLOG YKT6
(Rattus
norvegicus) 		4 / 6 ILE A 152
LEU A  94
PHE A  91
HIS A  67
 None
 0.99A 5vkqA-3kyqA:
undetectable
5vkqD-3kyqA:
undetectable		 5vkqA-3kyqA:
7.64
5vkqD-3kyqA:
7.64