SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 12 PHE A 136
LEU A 140
ILE A 147
ALA A  25
ALA A  23
 None
 1.01A 1cbsA-3kzaA:
3.1		 1cbsA-3kzaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 12 PHE A 136
LEU A 140
ILE A 147
ALA A  25
LEU A 103
 None
 0.93A 1cbsA-3kzaA:
3.1		 1cbsA-3kzaA:
22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		5 / 9 LEU A  39
LEU A  58
ILE A  71
VAL A  92
GLN A 120
 None
 0.61A 1gx8A-3kzaA:
26.4		 1gx8A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		5 / 9 LEU A  58
ILE A  71
VAL A  92
PHE A 105
GLN A 120
 None
 0.93A 1gx8A-3kzaA:
26.4		 1gx8A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 11 LEU A  39
VAL A  41
ILE A  56
LYS A  60
ILE A  71
GLN A 120
 None
 0.83A 1gx9A-3kzaA:
26.2		 1gx9A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 11 LEU A  39
VAL A  41
ILE A  56
LYS A  60
VAL A  92
GLN A 120
 None
 0.66A 1gx9A-3kzaA:
26.2		 1gx9A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 11 LEU A  39
VAL A  41
LYS A  60
VAL A  92
MET A 107
 None
 1.03A 1gx9A-3kzaA:
26.2		 1gx9A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 11 VAL A  41
ILE A  56
LYS A  60
ILE A  71
PHE A 105
GLN A 120
 None
 0.97A 1gx9A-3kzaA:
26.2		 1gx9A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 11 VAL A  41
ILE A  56
LYS A  60
VAL A  92
PHE A 105
GLN A 120
 None
 0.82A 1gx9A-3kzaA:
26.2		 1gx9A-3kzaA:
81.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 12 PHE A 136
LEU A 140
ILE A 147
ALA A  25
ALA A  23
 None
 1.02A 2fr3A-3kzaA:
2.5		 2fr3A-3kzaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 12 PHE A 136
LEU A 140
ILE A 147
ALA A  25
LEU A 103
 None
 0.97A 2g78A-3kzaA:
3.8		 2g78A-3kzaA:
21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 12 LEU A  39
VAL A  41
VAL A  43
ILE A  56
ILE A  84
PHE A 105
 None
 0.47A 2gj5A-3kzaA:
25.6		 2gj5A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		7 / 12 LEU A  39
VAL A  41
VAL A  43
ILE A  56
LEU A  58
ILE A  71
ILE A  84
 None
 0.72A 2gj5A-3kzaA:
25.6		 2gj5A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		4 / 5 ASP A 137
LEU A 140
MET A 145
ARG A 148
 None
 0.97A 2gj5A-3kzaA:
25.6		 2gj5A-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 9 LEU A  31
PRO A  38
GLU A  89
ASN A 109
ALA A 111
SER A 116
 None
 0.49A 4omwD-3kzaA:
28.9		 4omwD-3kzaA:
78.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 9 LEU A  31
PRO A  38
GLU A  89
ASN A 109
GLN A 115
SER A 116
 None
 0.76A 4omwD-3kzaA:
28.9		 4omwD-3kzaA:
78.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 9 LEU A  39
PRO A  38
ASN A 109
ALA A 111
SER A 116
 None
 1.48A 4omwD-3kzaA:
28.9		 4omwD-3kzaA:
78.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		4 / 5 LEU A 104
VAL A  15
VAL A  43
TYR A 102
 None
 1.06A 4r7iA-3kzaA:
undetectable		 4r7iA-3kzaA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		3 / 3 VAL A 123
PHE A 136
ARG A 148
 None
 0.93A 4xr4B-3kzaA:
undetectable		 4xr4B-3kzaA:
16.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		10 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
ILE A  71
ILE A  84
VAL A  92
VAL A  94
LEU A 103
PHE A 105
 None
 0.54A 4y0pA-3kzaA:
25.4		 4y0pA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		9 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
VAL A  92
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 0.53A 4y0pA-3kzaA:
25.4		 4y0pA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 12 LEU A  39
VAL A  41
LEU A  54
LYS A  60
LEU A 103
PHE A 105
 None
 0.89A 4y0pA-3kzaA:
25.4		 4y0pA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		7 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
LEU A  58
LYS A  60
MET A 107
 None
 1.05A 4y0qA-3kzaA:
25.2		 4y0qA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		7 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
LEU A  58
VAL A  92
MET A 107
 None
 0.80A 4y0qA-3kzaA:
25.2		 4y0qA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		9 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
LYS A  60
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 0.85A 4y0qA-3kzaA:
25.2		 4y0qA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		9 / 12 LEU A  39
VAL A  41
LEU A  54
ILE A  56
VAL A  92
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 0.56A 4y0qA-3kzaA:
25.2		 4y0qA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		6 / 12 LEU A  87
VAL A  92
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 1.31A 4y0qA-3kzaA:
25.2		 4y0qA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		7 / 12 VAL A  41
LEU A  46
LEU A  54
ILE A  56
ILE A  84
VAL A  92
PHE A 105
 None
 0.59A 4y0rA-3kzaA:
24.9		 4y0rA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		7 / 12 VAL A  41
LEU A  46
LEU A  54
ILE A  56
LEU A  58
ILE A  71
ILE A  84
 None
 0.72A 4y0rA-3kzaA:
24.9		 4y0rA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		6 / 12 VAL A  41
LEU A  46
LEU A  54
VAL A  92
PHE A 105
MET A 107
 None
 0.48A 4y0rA-3kzaA:
24.9		 4y0rA-3kzaA:
81.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		7 / 12 LEU A  46
LEU A  54
ILE A  56
ILE A  84
VAL A  92
LEU A 122
MET A 107
 None
 1.38A 4y0sA-3kzaA:
25.2		 4y0sA-3kzaA:
78.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		6 / 12 LEU A  54
ILE A  71
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 1.38A 4y0sA-3kzaA:
25.2		 4y0sA-3kzaA:
78.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Equus
caballus;
Bos
taurus) 		11 / 12 VAL A  41
LEU A  46
LEU A  54
ILE A  56
LYS A  60
ILE A  84
VAL A  92
VAL A  94
LEU A 103
PHE A 105
MET A 107
 None
 0.82A 4y0sA-3kzaA:
25.2		 4y0sA-3kzaA:
78.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		4 / 8 VAL A  41
LEU A  58
VAL A  92
MET A 107
 None
 0.66A 5nujA-3kzaA:
24.5		 5nujA-3kzaA:
75.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		5 / 10 VAL A  41
ILE A  84
VAL A  92
ALA A 118
GLN A 120
 None
 0.70A 5nukA-3kzaA:
25.3		 5nukA-3kzaA:
75.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3kza BETA-LACTOGLOBULIN
(Bos
taurus;
Equus
caballus) 		6 / 9 VAL A  41
ILE A  56
LEU A  58
ILE A  71
ILE A  84
ALA A 118
 None
 0.80A 5nunA-3kzaA:
25.5		 5nunA-3kzaA:
76.74