SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 LEU A 415
GLY A 196
GLY A 195
ALA A 357
LEU A 413
 None
 0.91A 1bx4A-3kzuA:
undetectable		 1bx4A-3kzuA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 6 LEU A 413
ARG A 365
TYR A 307
VAL A 246
 None
 1.10A 1db1A-3kzuA:
undetectable		 1db1A-3kzuA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.88A 1gtfN-3kzuA:
undetectable
1gtfO-3kzuA:
undetectable		 1gtfN-3kzuA:
10.51
1gtfO-3kzuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 GLY A 173
VAL A 166
ALA A 355
GLY A 114
HIS A 347
 None
 1.21A 1kiaB-3kzuA:
undetectable		 1kiaB-3kzuA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 GLY A 173
SER A 113
THR A 168
ALA A 357
ILE A 177
 None
 1.12A 1nt2A-3kzuA:
undetectable		 1nt2A-3kzuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 7 THR A 409
ALA A 411
LEU A 413
SER A 401
 None
 0.73A 1tyrB-3kzuA:
undetectable		 1tyrB-3kzuA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 PRO A 229
ILE A 336
TYR A 307
VAL A 325
LEU A 400
 None
 1.14A 1z9hD-3kzuA:
undetectable		 1z9hD-3kzuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 LEU A 386
LEU A 322
ILE A 308
ILE A 336
ALA A 333
 None
 1.04A 2bxcA-3kzuA:
undetectable		 2bxcA-3kzuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 LEU A 386
LEU A 322
ILE A 308
ILE A 336
ALA A 333
 None
 0.99A 2bxqA-3kzuA:
undetectable		 2bxqA-3kzuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 ASP A 179
GLY A 267
ILE A 266
ALA A 357
ILE A 177
 None
 1.01A 2idwA-3kzuA:
undetectable		 2idwA-3kzuA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 ILE A  52
ALA A 355
VAL A 358
PHE A  62
HIS A  67
 None
 1.38A 2qo4A-3kzuA:
0.2		 2qo4A-3kzuA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 10 LEU A 110
GLY A 108
GLY A 195
LEU A 248
ALA A 180
 None
 1.00A 2v3kA-3kzuA:
undetectable		 2v3kA-3kzuA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		6 / 12 GLY A 178
ILE A 184
ALA A 294
ALA A 298
VAL A   4
LEU A 415
 None
 1.29A 2yqzA-3kzuA:
undetectable		 2yqzA-3kzuA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		6 / 12 GLY A 178
ILE A 184
ALA A 294
ALA A 298
VAL A   4
LEU A 415
 None
 1.27A 2yqzB-3kzuA:
undetectable		 2yqzB-3kzuA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 ILE A 308
LEU A 295
ALA A 298
ILE A 300
ILE A 364
 None
 1.09A 3b2rA-3kzuA:
undetectable		 3b2rA-3kzuA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 ILE A 308
LEU A 295
ALA A 298
ILE A 300
ILE A 364
 None
 1.10A 3b2rB-3kzuA:
undetectable		 3b2rB-3kzuA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 VAL A 201
GLY A 240
ILE A 345
PRO A  14
PRO A  53
 None
 1.28A 3bjwF-3kzuA:
undetectable		 3bjwF-3kzuA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 VAL A 201
GLY A 240
ILE A 345
PRO A  14
PRO A  53
 None
 1.26A 3bjwH-3kzuA:
undetectable		 3bjwH-3kzuA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 6 LEU A  27
ALA A 371
LEU A  26
SER A 344
THR A 372
 None
 1.44A 3cfqA-3kzuA:
undetectable		 3cfqA-3kzuA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 7 LEU A  27
ALA A 371
LEU A  26
SER A 344
THR A 372
 None
 1.46A 3cfqA-3kzuA:
undetectable
3cfqB-3kzuA:
undetectable		 3cfqA-3kzuA:
15.42
3cfqB-3kzuA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 GLY A 116
GLY A 114
GLY A 350
THR A 197
ILE A 121
 None
 0.98A 3ihtA-3kzuA:
undetectable		 3ihtA-3kzuA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		3 / 3 SER A 340
GLY A 312
SER A 227
 None
 0.60A 3loqA-3kzuA:
undetectable		 3loqA-3kzuA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 LEU A 348
ALA A 310
GLY A  32
PRO A  14
 None
 0.93A 3ny4A-3kzuA:
undetectable		 3ny4A-3kzuA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 VAL A 193
ALA A 194
GLY A 195
LEU A  91
TYR A 262
 None
 1.19A 3rc0A-3kzuA:
undetectable		 3rc0A-3kzuA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 HIS A 253
VAL A 191
VAL A 247
ASP A 103
 None
 1.05A 3uy4A-3kzuA:
undetectable		 3uy4A-3kzuA:
20.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		12 / 12 GLY A 114
ALA A 169
CYH A 170
GLU A 198
SER A 205
PHE A 209
HIS A 311
THR A 313
HIS A 347
LEU A 349
GLY A 405
PHE A 406
 None
 0.65A 4ls7A-3kzuA:
67.6		 4ls7A-3kzuA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		8 / 12 GLY A 350
ALA A 169
CYH A 170
GLU A 198
PHE A 209
LEU A 349
GLY A 405
PHE A 406
 None
 1.50A 4ls7A-3kzuA:
67.6		 4ls7A-3kzuA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		6 / 12 GLY A 350
ALA A 169
CYH A 170
PHE A 237
HIS A 311
PHE A 406
 None
 1.13A 4ls7A-3kzuA:
67.6		 4ls7A-3kzuA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		10 / 12 ALA A 169
CYH A 170
SER A 205
PHE A 209
HIS A 311
THR A 313
HIS A 347
LEU A 349
GLY A 405
PHE A 406
 None
 0.70A 4ls7A-3kzuA:
67.6
4ls7B-3kzuA:
67.4		 4ls7A-3kzuA:
52.29
4ls7B-3kzuA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 ILE A 115
ALA A 169
CYH A 170
HIS A 311
GLY A 405
 None
 0.81A 4ls7A-3kzuA:
67.6
4ls7B-3kzuA:
67.4		 4ls7A-3kzuA:
52.29
4ls7B-3kzuA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 SER A 205
PHE A 209
THR A 315
GLY A 405
PHE A 406
 None
 1.08A 4ls7A-3kzuA:
67.6
4ls7B-3kzuA:
67.4		 4ls7A-3kzuA:
52.29
4ls7B-3kzuA:
52.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 7 TYR A  82
GLU A 198
GLU A 241
GLU A 119
 None
 0.99A 4mi4A-3kzuA:
undetectable
4mi4C-3kzuA:
undetectable		 4mi4A-3kzuA:
19.63
4mi4C-3kzuA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 LEU A 415
GLY A 196
GLY A 195
ALA A 357
LEU A 413
 None
 0.87A 4n09C-3kzuA:
undetectable		 4n09C-3kzuA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 6 THR A 409
ALA A 411
LEU A 413
SER A 401
 None
 1.05A 4pwjA-3kzuA:
undetectable		 4pwjA-3kzuA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.43A 4qvlV-3kzuA:
undetectable
4qvlb-3kzuA:
undetectable		 4qvlV-3kzuA:
21.26
4qvlb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.43A 4qvlH-3kzuA:
undetectable
4qvlN-3kzuA:
undetectable		 4qvlH-3kzuA:
21.26
4qvlN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 4qvmV-3kzuA:
undetectable
4qvmb-3kzuA:
undetectable		 4qvmV-3kzuA:
21.26
4qvmb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 4qvmH-3kzuA:
undetectable
4qvmN-3kzuA:
undetectable		 4qvmH-3kzuA:
21.26
4qvmN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.47A 4qvpV-3kzuA:
undetectable
4qvpb-3kzuA:
undetectable		 4qvpV-3kzuA:
21.26
4qvpb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.47A 4qvpH-3kzuA:
undetectable
4qvpN-3kzuA:
undetectable		 4qvpH-3kzuA:
21.26
4qvpN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.47A 4qvqV-3kzuA:
undetectable
4qvqb-3kzuA:
undetectable		 4qvqV-3kzuA:
21.26
4qvqb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.48A 4qvqH-3kzuA:
undetectable
4qvqN-3kzuA:
undetectable		 4qvqH-3kzuA:
21.26
4qvqN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.43A 4qvwV-3kzuA:
undetectable
4qvwb-3kzuA:
undetectable		 4qvwV-3kzuA:
21.26
4qvwb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.43A 4qvwH-3kzuA:
undetectable
4qvwN-3kzuA:
undetectable		 4qvwH-3kzuA:
21.26
4qvwN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.44A 4qw0V-3kzuA:
undetectable
4qw0b-3kzuA:
undetectable		 4qw0V-3kzuA:
21.26
4qw0b-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.44A 4qw0H-3kzuA:
undetectable
4qw0N-3kzuA:
undetectable		 4qw0H-3kzuA:
21.26
4qw0N-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 4qw1V-3kzuA:
undetectable
4qw1b-3kzuA:
undetectable		 4qw1V-3kzuA:
21.26
4qw1b-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.44A 4qw1H-3kzuA:
undetectable
4qw1N-3kzuA:
undetectable		 4qw1H-3kzuA:
21.26
4qw1N-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 4qw3V-3kzuA:
undetectable
4qw3b-3kzuA:
undetectable		 4qw3V-3kzuA:
21.26
4qw3b-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 4qw3H-3kzuA:
undetectable
4qw3N-3kzuA:
undetectable		 4qw3H-3kzuA:
21.26
4qw3N-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.46A 4qwuV-3kzuA:
undetectable
4qwub-3kzuA:
undetectable		 4qwuV-3kzuA:
21.26
4qwub-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.46A 4qwuH-3kzuA:
undetectable
4qwuN-3kzuA:
undetectable		 4qwuH-3kzuA:
21.26
4qwuN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 10 TYR A 268
LEU A 413
ALA A 243
ALA A 194
GLY A 353
 None
 1.40A 4rn6A-3kzuA:
undetectable		 4rn6A-3kzuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		3 / 3 GLU A 119
TYR A  82
GLU A 241
 None
 0.73A 4ryaA-3kzuA:
undetectable		 4ryaA-3kzuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 9 ALA A 243
ALA A  83
ALA A 149
SER A 150
SER A 165
 None
 1.32A 4twdA-3kzuA:
undetectable
4twdB-3kzuA:
undetectable
4twdC-3kzuA:
undetectable
4twdD-3kzuA:
undetectable
4twdE-3kzuA:
undetectable		 4twdA-3kzuA:
20.91
4twdB-3kzuA:
20.91
4twdC-3kzuA:
20.91
4twdD-3kzuA:
20.91
4twdE-3kzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 9 ALA A 351
ALA A 355
ALA A 357
SER A 401
SER A 403
 None
 1.33A 4twdA-3kzuA:
undetectable
4twdB-3kzuA:
undetectable
4twdC-3kzuA:
undetectable
4twdD-3kzuA:
undetectable
4twdE-3kzuA:
undetectable		 4twdA-3kzuA:
20.91
4twdB-3kzuA:
20.91
4twdC-3kzuA:
20.91
4twdD-3kzuA:
20.91
4twdE-3kzuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 9 LEU A   9
GLY A   8
ILE A 364
VAL A 358
THR A 361
 None
 1.45A 4x3mA-3kzuA:
undetectable		 4x3mA-3kzuA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 ALA A 194
GLY A 178
LEU A 362
LEU A   9
THR A 361
 None
 1.07A 4zmeA-3kzuA:
undetectable		 4zmeA-3kzuA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 7 ALA A 149
ASP A 179
GLY A 173
THR A 409
 None
 0.97A 5bs8A-3kzuA:
undetectable
5bs8B-3kzuA:
undetectable
5bs8C-3kzuA:
undetectable		 5bs8A-3kzuA:
22.58
5bs8B-3kzuA:
22.74
5bs8C-3kzuA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.44A 5bxnV-3kzuA:
undetectable
5bxnb-3kzuA:
undetectable		 5bxnV-3kzuA:
21.18
5bxnb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 5bxnH-3kzuA:
undetectable
5bxnN-3kzuA:
undetectable		 5bxnH-3kzuA:
21.18
5bxnN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 5cz7H-3kzuA:
undetectable
5cz7N-3kzuA:
undetectable		 5cz7H-3kzuA:
21.26
5cz7N-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.45A 5d0xV-3kzuA:
undetectable
5d0xb-3kzuA:
undetectable		 5d0xV-3kzuA:
21.26
5d0xb-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.46A 5d0xH-3kzuA:
undetectable
5d0xN-3kzuA:
undetectable		 5d0xH-3kzuA:
21.26
5d0xN-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.90A 5eevL-3kzuA:
undetectable
5eevV-3kzuA:
undetectable		 5eevL-3kzuA:
10.51
5eevV-3kzuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.90A 5eewL-3kzuA:
undetectable
5eewV-3kzuA:
undetectable		 5eewL-3kzuA:
10.51
5eewV-3kzuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 8 HIS A 311
ALA A 214
THR A 315
THR A 313
 None
 0.90A 5ef3L-3kzuA:
undetectable
5ef3V-3kzuA:
undetectable		 5ef3L-3kzuA:
10.51
5ef3V-3kzuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 LEU A 415
GLY A 196
GLY A 195
ALA A 357
LEU A 413
 None
 0.92A 5kb5A-3kzuA:
undetectable		 5kb5A-3kzuA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.47A 5l66V-3kzuA:
undetectable
5l66b-3kzuA:
undetectable		 5l66V-3kzuA:
21.26
5l66b-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 11 THR A 197
THR A 172
THR A 174
GLY A 244
ALA A 355
 None
 1.47A 5l66H-3kzuA:
undetectable
5l66N-3kzuA:
undetectable		 5l66H-3kzuA:
21.26
5l66N-3kzuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 10 GLU A 304
LEU A 248
ALA A 298
THR A 174
LEU A 400
 None
 1.45A 5mm4B-3kzuA:
undetectable		 5mm4B-3kzuA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		4 / 5 TYR A 268
SER A 412
ALA A 411
THR A 409
 None
 1.30A 5n0tA-3kzuA:
undetectable		 5n0tA-3kzuA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 10 GLN A  89
LEU A 348
GLY A 196
VAL A  12
ALA A 355
 None
 1.18A 5o96E-3kzuA:
undetectable
5o96F-3kzuA:
undetectable		 5o96E-3kzuA:
19.91
5o96F-3kzuA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 ALA A 149
ARG A 144
GLY A 116
GLY A 114
MET A 239
 None
 1.22A 5ul4A-3kzuA:
undetectable		 5ul4A-3kzuA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 GLY A 242
ALA A 354
PRO A  14
PHE A  62
VAL A 201
 None
 1.20A 5x6yA-3kzuA:
undetectable		 5x6yA-3kzuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 GLY A 408
PRO A 280
ALA A 279
ASP A 273
THR A 409
 None
 1.06A 5x6yC-3kzuA:
undetectable		 5x6yC-3kzuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II
(Brucella
melitensis) 		5 / 12 VAL A  54
THR A  61
GLY A  57
VAL A  81
TYR A  82
 None
 1.12A 6drzA-3kzuA:
undetectable		 6drzA-3kzuA:
22.18