SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.88A 1p7rA-3l06A:
undetectable		 1p7rA-3l06A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 PRO A  72
THR A 145
ILE A 109
LEU A 102
VAL A  98
 None
 1.13A 1r30A-3l06A:
undetectable		 1r30A-3l06A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 PRO A  72
THR A 145
ILE A 109
LEU A 102
VAL A  98
 None
 1.14A 1r30B-3l06A:
undetectable		 1r30B-3l06A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.74A 1t87B-3l06A:
undetectable		 1t87B-3l06A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  58
GLY A  59
GLN A  62
MET A 330
ILE A 329
 None
 1.19A 1z95A-3l06A:
undetectable		 1z95A-3l06A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 6 LEU A   7
ASN A   8
LEU A 153
ILE A 195
 None
 1.02A 1z95A-3l06A:
undetectable		 1z95A-3l06A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  26
HIS A 324
ALA A 331
GLY A  33
GLU A  35
 None
 1.21A 2a58A-3l06A:
2.5
2a58B-3l06A:
4.9		 2a58A-3l06A:
18.36
2a58B-3l06A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  26
HIS A 324
ALA A 331
GLY A  33
GLU A  35
 None
 1.20A 2a58B-3l06A:
4.9
2a58C-3l06A:
4.9		 2a58B-3l06A:
18.36
2a58C-3l06A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  26
HIS A 324
ALA A 331
GLY A  33
GLU A  35
 None
 1.21A 2a58D-3l06A:
2.5
2a58E-3l06A:
2.5		 2a58D-3l06A:
18.36
2a58E-3l06A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 8 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.74A 2qbmA-3l06A:
undetectable		 2qbmA-3l06A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 5 LEU A 108
GLN A 326
HIS A   5
LEU A   7
 None
 1.04A 3ce6D-3l06A:
2.1		 3ce6D-3l06A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 8 GLY A 245
ALA A 246
ASP A 247
THR A 176
 None
 0.66A 3el0A-3l06A:
undetectable		 3el0A-3l06A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 PRO A 268
ASP A 271
GLU A 266
 None
 0.84A 3v4tC-3l06A:
undetectable		 3v4tC-3l06A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A 193
LEU A 205
LEU A 206
MET A 219
THR A 197
 None
 1.32A 4fn9B-3l06A:
undetectable		 4fn9B-3l06A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 11 LEU A 214
LEU A 206
CYH A 207
TRP A 254
ALA A 189
 None
 1.30A 4hwkB-3l06A:
undetectable		 4hwkB-3l06A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 8 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.75A 4l4cB-3l06A:
undetectable		 4l4cB-3l06A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  58
GLY A  59
GLN A  62
MET A 330
ILE A 329
 None
 1.16A 4oktA-3l06A:
undetectable		 4oktA-3l06A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 LEU A  58
GLY A  59
GLN A  62
MET A 330
ILE A 329
 None
 1.20A 4okwA-3l06A:
undetectable		 4okwA-3l06A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 7 LEU A   7
ASN A   8
LEU A 153
ILE A 195
 None
 0.92A 4okwA-3l06A:
undetectable		 4okwA-3l06A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 9 PRO A  72
ILE A  95
VAL A  98
ALA A  99
ALA A  42
 None
 1.11A 4oqrA-3l06A:
undetectable		 4oqrA-3l06A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 9 PRO A  72
VAL A  69
ILE A  95
VAL A  98
ALA A  99
 None
 1.14A 4oqrA-3l06A:
undetectable		 4oqrA-3l06A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		3 / 3 THR A 304
ASP A 305
ALA A 306
 None
 0.10A 5g5gB-3l06A:
undetectable		 5g5gB-3l06A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		5 / 12 GLU A 228
VAL A 226
THR A 194
ARG A 198
GLU A 152
 None
 1.11A 5xipD-3l06A:
2.2		 5xipD-3l06A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE
(Xanthomonas
campestris) 		4 / 6 ARG A 322
ILE A 141
MET A 143
ASN A 142
 CP  A 346 (-3.5A)
None
None
None
 1.40A 6dhbA-3l06A:
undetectable		 6dhbA-3l06A:
15.85