SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l0a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DTJ_B_THRB402_0 (ASPARTOKINASE)	3l0a	PUTATIVE EXONUCLEASE ([Eubacterium] rectale)	5 / 9	ILE A 205 ILE A 100 ASP A 103 GLY A 194 ALA A 193	None	1.19A	2dtjA-3l0aA: undetectable 2dtjB-3l0aA: undetectable	2dtjA-3l0aA: 20.59 2dtjB-3l0aA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3B_B_FOLB401_1 (DIHYDROFOLATE REDUCTASE)	3l0a	PUTATIVE EXONUCLEASE ([Eubacterium] rectale)	3 / 3	GLU A 221 GLN A 182 ARG A 181	None	0.93A	2w3bB-3l0aA: undetectable	2w3bB-3l0aA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB401_0 (GLYCINE OXIDASE)	3l0a	PUTATIVE EXONUCLEASE ([Eubacterium] rectale)	4 / 6	PHE A 72 GLY A 58 TYR A 60 ALA A 93	None	1.18A	4yshB-3l0aA: undetectable	4yshB-3l0aA: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NM4_B_SAMB402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9)	3l0a	PUTATIVE EXONUCLEASE ([Eubacterium] rectale)	5 / 9	ILE A 203 ALA A 195 GLY A 194 GLY A 58 ARG A 99	None	1.16A	6nm4B-3l0aA: undetectable	6nm4B-3l0aA: 20.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DTJ_B_THRB402_0","ASPARTOKINASE","3l0a","PUTATIVE EXONUCLEASE","[Eubacterium] rectale",5,"ILE A 205;ILE A 100;ASP A 103;GLY A 194;ALA A 193","None","1.19A","2dtjA-3l0aA:undetectable;2dtjB-3l0aA:undetectable","2dtjA-3l0aA:20.59;2dtjB-3l0aA:20.59"],["2W3B_B_FOLB401_1","DIHYDROFOLATE REDUCTASE","3l0a","PUTATIVE EXONUCLEASE","[Eubacterium] rectale",3,"GLU A 221;GLN A 182;ARG A 181","None","0.93A","2w3bB-3l0aA:undetectable","2w3bB-3l0aA:20.61"],["4YSH_B_GLYB401_0","GLYCINE OXIDASE","3l0a","PUTATIVE EXONUCLEASE","[Eubacterium] rectale",4,"PHE A  72;GLY A  58;TYR A  60;ALA A  93","None","1.18A","4yshB-3l0aA:undetectable","4yshB-3l0aA:22.05"],["6NM4_B_SAMB402_0","HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9","3l0a","PUTATIVE EXONUCLEASE","[Eubacterium] rectale",5,"ILE A 203;ALA A 195;GLY A 194;GLY A  58;ARG A  99","None","1.16A","6nm4B-3l0aA:undetectable","6nm4B-3l0aA:20.15"]]