SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		6 / 7 SER A 152
THR A 154
ASN A 156
CYH A 157
TYR A 314
ASN A 316
 None
None
None
None
None
NAD  A 336 (-3.9A)
 0.21A 1dssG-3l0dA:
48.2		 1dssG-3l0dA:
44.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		7 / 8 SER A 152
THR A 154
ASN A 156
CYH A 157
HIS A 180
TYR A 314
ASN A 316
 None
None
None
None
None
None
NAD  A 336 (-3.9A)
 0.37A 1dssR-3l0dA:
48.0		 1dssR-3l0dA:
44.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.83A 1fbmD-3l0dA:
undetectable		 1fbmD-3l0dA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 5 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.63A 1fbmE-3l0dA:
undetectable		 1fbmE-3l0dA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 12 VAL A 217
GLY A 212
LEU A 245
THR A 178
THR A 155
 None
 1.05A 2egvA-3l0dA:
3.1		 2egvA-3l0dA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		6 / 11 LEU A  96
ILE A  17
GLY A  14
GLY A  11
LEU A 120
SER A 149
 None
None
None
NAD  A 336 (-2.6A)
None
None
 1.03A 2qmmA-3l0dA:
2.8
2qmmB-3l0dA:
2.7		 2qmmA-3l0dA:
20.39
2qmmB-3l0dA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 9 LEU A  96
ILE A  17
GLY A  14
LEU A 120
SER A 149
 None
 0.98A 3ai9X-3l0dA:
2.3		 3ai9X-3l0dA:
19.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		7 / 8 SER A 152
THR A 154
ASN A 156
CYH A 157
HIS A 180
TYR A 314
ASN A 316
 None
None
None
None
None
None
NAD  A 336 (-3.9A)
 0.33A 3dmtC-3l0dA:
47.4		 3dmtC-3l0dA:
44.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 5 HIS A 180
SER A 232
SER A 210
VAL A 231
 None
 1.28A 4a99D-3l0dA:
4.2		 4a99D-3l0dA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		3 / 3 ASN A 239
ASP A 315
ASN A 316
 None
None
NAD  A 336 (-3.9A)
 0.71A 4agaA-3l0dA:
undetectable		 4agaA-3l0dA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 11 SER A 122
ILE A  13
ASP A 315
GLY A 319
PHE A 320
 NAD  A 336 (-3.4A)
NAD  A 336 (-3.8A)
None
None
NAD  A 336 (-3.6A)
 1.31A 4fogA-3l0dA:
undetectable		 4fogA-3l0dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 11 SER A 122
ILE A  13
ASP A 315
GLY A 319
PHE A 320
 NAD  A 336 (-3.4A)
NAD  A 336 (-3.8A)
None
None
NAD  A 336 (-3.6A)
 1.26A 4fogC-3l0dA:
undetectable		 4fogC-3l0dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 12 SER A 122
ILE A  13
ASP A 315
GLY A 319
PHE A 320
 NAD  A 336 (-3.4A)
NAD  A 336 (-3.8A)
None
None
NAD  A 336 (-3.6A)
 1.29A 4foxE-3l0dA:
undetectable		 4foxE-3l0dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 11 SER A 122
ILE A  13
ASP A 315
GLY A 319
PHE A 320
 NAD  A 336 (-3.4A)
NAD  A 336 (-3.8A)
None
None
NAD  A 336 (-3.6A)
 1.25A 4foxH-3l0dA:
undetectable		 4foxH-3l0dA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 8 GLY A 319
ASN A 322
ARG A  26
ILE A 273
 None
 0.97A 4j4vC-3l0dA:
undetectable		 4j4vC-3l0dA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 7 THR A 183
ARG A 198
SER A 232
HIS A 180
 None
 1.30A 4o4dA-3l0dA:
1.0		 4o4dA-3l0dA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 11 SER A 152
LEU A 158
PRO A 160
VAL A 133
THR A 131
 None
 1.18A 4uuuB-3l0dA:
undetectable		 4uuuB-3l0dA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 6 ARG A  12
ASP A  50
VAL A 240
ASP A 315
 None
 1.39A 4xqeA-3l0dA:
10.7		 4xqeA-3l0dA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		4 / 6 ARG A  12
ASP A  50
VAL A 240
ASP A 315
 None
 1.39A 4xqeB-3l0dA:
10.7		 4xqeB-3l0dA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 10 LEU A 221
LEU A 224
LEU A 228
THR A 155
LEU A 158
 None
 0.97A 4z91A-3l0dA:
undetectable
4z91B-3l0dA:
undetectable
4z91C-3l0dA:
undetectable
4z91D-3l0dA:
undetectable
4z91E-3l0dA:
undetectable		 4z91A-3l0dA:
21.07
4z91B-3l0dA:
21.07
4z91C-3l0dA:
21.07
4z91D-3l0dA:
21.07
4z91E-3l0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 10 LEU A 221
LEU A 224
LEU A 228
THR A 155
LEU A 158
 None
 1.03A 4z91A-3l0dA:
undetectable
4z91B-3l0dA:
undetectable
4z91C-3l0dA:
undetectable
4z91D-3l0dA:
undetectable
4z91E-3l0dA:
undetectable		 4z91A-3l0dA:
21.07
4z91B-3l0dA:
21.07
4z91C-3l0dA:
21.07
4z91D-3l0dA:
21.07
4z91E-3l0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 10 LEU A 224
LEU A 228
THR A 155
LEU A 158
LEU A 221
 None
 0.97A 4z91A-3l0dA:
undetectable
4z91B-3l0dA:
undetectable
4z91C-3l0dA:
undetectable
4z91D-3l0dA:
undetectable
4z91E-3l0dA:
undetectable		 4z91A-3l0dA:
21.07
4z91B-3l0dA:
21.07
4z91C-3l0dA:
21.07
4z91D-3l0dA:
21.07
4z91E-3l0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 10 LEU A 228
THR A 155
LEU A 158
LEU A 221
LEU A 224
 None
 0.99A 4z91A-3l0dA:
undetectable
4z91B-3l0dA:
undetectable
4z91C-3l0dA:
undetectable
4z91D-3l0dA:
undetectable
4z91E-3l0dA:
undetectable		 4z91A-3l0dA:
21.07
4z91B-3l0dA:
21.07
4z91C-3l0dA:
21.07
4z91D-3l0dA:
21.07
4z91E-3l0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 10 THR A 155
LEU A 158
LEU A 221
LEU A 224
LEU A 228
 None
 1.03A 4z91A-3l0dA:
undetectable
4z91B-3l0dA:
undetectable
4z91C-3l0dA:
undetectable
4z91D-3l0dA:
undetectable
4z91E-3l0dA:
undetectable		 4z91A-3l0dA:
21.07
4z91B-3l0dA:
21.07
4z91C-3l0dA:
21.07
4z91D-3l0dA:
21.07
4z91E-3l0dA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 11 SER A 149
THR A 154
THR A 155
ALA A 123
THR A 103
 None
None
None
NAD  A 336 (-3.3A)
None
 1.48A 5bxnH-3l0dA:
undetectable
5bxnN-3l0dA:
undetectable		 5bxnH-3l0dA:
21.47
5bxnN-3l0dA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		3 / 3 THR A 155
ALA A 151
ASN A 156
 None
 0.58A 5ersA-3l0dA:
undetectable		 5ersA-3l0dA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		5 / 12 LEU A  96
ILE A  17
GLY A  14
LEU A 120
MET A 324
 None
 0.87A 5nfjA-3l0dA:
3.2		 5nfjA-3l0dA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(Bartonella
henselae) 		3 / 3 ARG A  19
HIS A  53
ARG A  12
 None
 1.14A 6dwdD-3l0dA:
undetectable		 6dwdD-3l0dA:
22.26