SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		5 / 12 LEU A  69
LEU A  95
ILE A  34
HIS A  38
LEU A  45
 None
 1.10A 1g50B-3l0sA:
undetectable		 1g50B-3l0sA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		5 / 11 LEU A  69
LEU A  95
ILE A  34
HIS A  38
LEU A  45
 None
 1.10A 1g50C-3l0sA:
undetectable		 1g50C-3l0sA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		5 / 10 LEU A  69
LEU A  95
ILE A  34
HIS A  38
LEU A  45
 None
 1.22A 1pcgA-3l0sA:
undetectable		 1pcgA-3l0sA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		5 / 12 GLY A  33
SER A  11
ILE A 112
GLY A  17
ILE A   5
 None
TAR  A 225 (-3.3A)
None
None
None
 1.05A 1q8jB-3l0sA:
undetectable		 1q8jB-3l0sA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		4 / 7 ALA A 188
TYR A 202
TYR A 189
TYR A 177
 None
 1.18A 2pncA-3l0sA:
undetectable		 2pncA-3l0sA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		5 / 10 ILE A 106
TYR A 190
LEU A  69
VAL A  68
LEU A  72
 None
 1.33A 2w98A-3l0sA:
undetectable		 2w98A-3l0sA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		4 / 6 GLU A 111
GLY A   7
LEU A 185
TYR A 178
 None
 0.94A 3w9tB-3l0sA:
undetectable		 3w9tB-3l0sA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		4 / 6 GLU A 111
GLY A   7
LEU A 185
TYR A 178
 None
 0.93A 3w9tE-3l0sA:
undetectable		 3w9tE-3l0sA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		4 / 6 GLU A 111
GLY A   7
LEU A 185
TYR A 178
 None
 0.93A 3w9tF-3l0sA:
undetectable		 3w9tF-3l0sA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3l0s ADENYLATE KINASE
(Desulfovibrio
gigas) 		4 / 7 LEU A  72
LEU A  69
ALA A  98
LEU A  82
 None
 0.67A 4z90F-3l0sA:
undetectable
4z90G-3l0sA:
undetectable
4z90H-3l0sA:
undetectable
4z90J-3l0sA:
undetectable		 4z90F-3l0sA:
22.01
4z90G-3l0sA:
22.01
4z90H-3l0sA:
22.01
4z90J-3l0sA:
22.01