SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 GLN B  31
GLU B  34
ILE B  36
PRO B  37
 None
 1.03A 2fcnA-3l0wB:
13.4
2fcnB-3l0wB:
13.2		 2fcnA-3l0wB:
93.42
2fcnB-3l0wB:
93.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.66A 4w5oA-3l0wB:
undetectable		 4w5oA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.59A 4w5qA-3l0wB:
undetectable		 4w5qA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.68A 4w5tA-3l0wB:
undetectable		 4w5tA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.60A 4z4cA-3l0wB:
undetectable		 4z4cA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.64A 4z4dA-3l0wB:
undetectable		 4z4dA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.64A 4z4eA-3l0wB:
undetectable		 4z4eA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.65A 4z4gA-3l0wB:
undetectable		 4z4gA-3l0wB:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3l0w MONOUBIQUITINATED
PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.70A 6cbdA-3l0wB:
undetectable		 6cbdA-3l0wB:
11.64