SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 5 GLU A   8
ARG A  14
ASP A  86
ASP A 109
 None
 1.20A 2yqzA-3l10A:
undetectable		 2yqzA-3l10A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 5 GLU A   8
ARG A  14
ASP A  86
ASP A 109
 None
 1.21A 2yqzB-3l10A:
undetectable		 2yqzB-3l10A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  99
LEU A 116
LEU A  72
VAL A  48
 None
 0.89A 3r9vA-3l10A:
undetectable
3r9vB-3l10A:
undetectable		 3r9vA-3l10A:
22.64
3r9vB-3l10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  15
ILE A  16
LEU A  90
LEU A 101
ILE A  99
 None
 1.12A 3uvvA-3l10A:
undetectable		 3uvvA-3l10A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		5 / 11 ALA A   4
LEU A  88
PHE A  12
LYS A  13
LEU A  75
 None
 1.38A 4i1nA-3l10A:
undetectable		 4i1nA-3l10A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		5 / 12 LEU A   2
PRO A  96
MET A  70
GLY A  69
LEU A 118
 None
 1.29A 4j7xB-3l10A:
undetectable		 4j7xB-3l10A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  35
LEU A  72
ILE A  16
LEU A  79
GLY A  82
 None
 1.00A 5ienA-3l10A:
undetectable		 5ienA-3l10A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  63
ARG A  61
ASP A  93
 None
 0.79A 5zvgA-3l10A:
undetectable		 5zvgA-3l10A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  63
ARG A  61
ASP A  93
 None
 0.76A 5zvgB-3l10A:
undetectable		 5zvgB-3l10A:
19.58