SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3l15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		4 / 5 SER A 344
GLY A 284
GLU A 356
CYH A 348
 None
 1.06A 3aiaA-3l15A:
undetectable
3aiaB-3l15A:
undetectable		 3aiaA-3l15A:
22.80
3aiaB-3l15A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		4 / 6 LEU A 374
GLU A 359
SER A 331
PHE A 233
 None
 1.43A 3i9jB-3l15A:
undetectable		 3i9jB-3l15A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 12 LEU A 230
SER A 331
ILE A 254
PHE A 251
SER A 377
 None
 1.12A 3ko0A-3l15A:
undetectable
3ko0B-3l15A:
undetectable
3ko0C-3l15A:
undetectable
3ko0D-3l15A:
undetectable		 3ko0A-3l15A:
20.36
3ko0B-3l15A:
20.36
3ko0C-3l15A:
20.36
3ko0D-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 11 LEU A 230
SER A 331
ILE A 254
PHE A 251
SER A 377
 None
 1.17A 3ko0C-3l15A:
undetectable
3ko0D-3l15A:
undetectable
3ko0E-3l15A:
undetectable
3ko0F-3l15A:
undetectable		 3ko0C-3l15A:
20.36
3ko0D-3l15A:
20.36
3ko0E-3l15A:
20.36
3ko0F-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 12 SER A 377
LEU A 230
SER A 331
ILE A 254
PHE A 251
 None
 1.15A 3ko0G-3l15A:
undetectable
3ko0H-3l15A:
undetectable
3ko0I-3l15A:
undetectable
3ko0J-3l15A:
undetectable		 3ko0G-3l15A:
20.36
3ko0H-3l15A:
20.36
3ko0I-3l15A:
20.36
3ko0J-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 11 SER A 377
LEU A 230
SER A 331
ILE A 254
PHE A 251
 None
 1.18A 3ko0A-3l15A:
undetectable
3ko0B-3l15A:
undetectable
3ko0I-3l15A:
undetectable
3ko0J-3l15A:
undetectable		 3ko0A-3l15A:
20.36
3ko0B-3l15A:
20.36
3ko0I-3l15A:
20.36
3ko0J-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 12 LEU A 230
SER A 331
ILE A 254
PHE A 251
SER A 377
 None
 1.15A 3ko0K-3l15A:
undetectable
3ko0L-3l15A:
undetectable
3ko0S-3l15A:
undetectable
3ko0T-3l15A:
undetectable		 3ko0K-3l15A:
20.36
3ko0L-3l15A:
20.36
3ko0S-3l15A:
20.36
3ko0T-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 12 LEU A 230
SER A 331
ILE A 254
PHE A 251
SER A 377
 None
 1.14A 3ko0K-3l15A:
undetectable
3ko0L-3l15A:
undetectable
3ko0M-3l15A:
undetectable
3ko0N-3l15A:
undetectable		 3ko0K-3l15A:
20.36
3ko0L-3l15A:
20.36
3ko0M-3l15A:
20.36
3ko0N-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 11 LEU A 230
SER A 331
ILE A 254
PHE A 251
SER A 377
 None
 1.09A 3ko0O-3l15A:
undetectable
3ko0P-3l15A:
undetectable
3ko0Q-3l15A:
undetectable
3ko0R-3l15A:
undetectable		 3ko0O-3l15A:
20.36
3ko0P-3l15A:
20.36
3ko0Q-3l15A:
20.36
3ko0R-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 12 SER A 377
LEU A 230
SER A 331
ILE A 254
PHE A 251
 None
 1.15A 3ko0M-3l15A:
undetectable
3ko0N-3l15A:
undetectable
3ko0O-3l15A:
undetectable
3ko0P-3l15A:
undetectable		 3ko0M-3l15A:
20.36
3ko0N-3l15A:
20.36
3ko0O-3l15A:
20.36
3ko0P-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 10 SER A 377
LEU A 230
SER A 331
ILE A 254
PHE A 251
 None
 1.12A 3ko0O-3l15A:
undetectable
3ko0P-3l15A:
undetectable
3ko0Q-3l15A:
undetectable
3ko0R-3l15A:
undetectable		 3ko0O-3l15A:
20.36
3ko0P-3l15A:
20.36
3ko0Q-3l15A:
20.36
3ko0R-3l15A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 8 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.37A 3v81C-3l15A:
undetectable		 3v81C-3l15A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 9 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.47A 4puoA-3l15A:
undetectable		 4puoA-3l15A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 8 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.36A 4puoC-3l15A:
undetectable		 4puoC-3l15A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 9 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.35A 4q0bC-3l15A:
undetectable		 4q0bC-3l15A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		3 / 3 ARG A 373
GLN A 364
GLU A 366
 None
 0.90A 4tvtA-3l15A:
undetectable		 4tvtA-3l15A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 11 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.45A 5hbmA-3l15A:
undetectable		 5hbmA-3l15A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 10 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.49A 6bsgA-3l15A:
undetectable		 6bsgA-3l15A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 10 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.47A 6bsiA-3l15A:
undetectable		 6bsiA-3l15A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4
(Homo
sapiens) 		5 / 10 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.40A 6bsjA-3l15A:
undetectable		 6bsjA-3l15A:
17.11